Incontinence and MRI Results in Children with Cerebral Palsy

NCT ID: NCT05060211

Last Updated: 2024-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

125 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-25

Study Completion Date

2023-06-30

Brief Summary

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More than 50 % of children and adults with cerebral palsy experience lower urinary tract symptoms (LUTS). This can negatively influence quality of life of the child and the total social environment.

Previous research demonstrated that the brain lesion, characteristic for cerebral palsy (CP), is a prognostic factor for the functional abilities of a child with CP. Previous research within our department demonstrated functional impairment as a risk factor for incontinence. This demonstrates an indirect connection between the brain lesion and incontinence of a child with CP. However, this connection isn't alway correct as some children with high functionality also demonstrate incontinence.

As bladder control is also regulated by higher brain centers, the present study wants to investigate a direct connection between the brain lesion of the child, visible by means of MRI, and the incontinence status of the child. .

Detailed Description

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The current study is a cross-sectional observational study in which a correlation is investigated between known anatomical MRI results and the continence status of a child with CP.

Although neuroimaging isn't seen as a requirement for the definition and diagnosis of CP2, MRI imaging is often part of diagnostic evaluation. The Surveillance of Cerebral Palsy in Europe (SCPE) working group composed the MRI classification system or MRICS classifying neuroimaging results in maldevelopments, predominant white matter injury, predominant grey matter injury, miscellaneous and normal. These results will be correlated with results of the validated Vancouver symptoms score for dysfunctional elimination syndrome.

Conditions

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Cerebral Palsy Lower Urinary Tract Symptoms

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Vancouver symptom score for dysfunctional elimination syndroms

Validated questionnaire concerning bladder and bowel symptoms

Intervention Type OTHER

Magnetic resonance imaging

Known MRI results of the patient file

Intervention Type OTHER

Other Intervention Names

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VSSDES MRI

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of cerebral palsy
* MRI investigation in history
* Dutch or French speaking child and parent

Exclusion Criteria

* No MRI investigation in history
* Child or parent not speaking Dutch or French
Minimum Eligible Age

5 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Ghent

OTHER

Sponsor Role collaborator

University Hospital, Ghent

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bieke Samijn, dr.

Role: PRINCIPAL_INVESTIGATOR

Ghent University Hospital/Ghent University

Locations

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Ghent University Hospital

Ghent, Flanders, Belgium

Site Status

Countries

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Belgium

Other Identifiers

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B6702021000735

Identifier Type: -

Identifier Source: org_study_id

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