CRP and S&A for Inpatient Veterans

NCT ID: NCT05054738

Last Updated: 2025-05-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

195 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-06

Study Completion Date

2026-09-30

Brief Summary

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The purpose of this study is to evaluate how well three types of treatments work to improve the outcomes for people with substance use problems. Veterans admitted to the Charleston VA Psychiatric inpatient unit may be invited to participate. The three types of treatments that will be evaluated are:

1. Combined Recovery Program (CRP), a six-session treatment group delivered on the inpatient unit.
2. A Home Telehealth program, called Stable and Able (S\&A), provided just prior to discharge and provides additional support for up to 3 months
3. Treatment-as-usual (TAU), which is the treatment currently provided on the unit, consisting of various mental health topics and sessions designed to help with recovery.

Participation begins on the inpatient unit, beginning with CRP and/or TAU, and may continue with S\&A post discharge. Participants will be followed up at 1 and 3- months post treatment.

Detailed Description

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Background:

High inpatient readmissions among Veterans with substance use disorders (SUD) constitutes a costly and persistent healthcare problem. Studies demonstrate that patients with SUDs return to inpatient treatment multiple times and that high inpatient service utilization in this population is associated with high rates of co-occurring mental illness (SUD/MI), homelessness, suicidality, and continued impairment in health and social functioning. A significant proportion (21%) of Veterans with SUD/MI are homeless, at high-risk for suicide, and represent one of the largest, most chronic groups of psychiatric patients treated in the VA Healthcare System. In effort to ameliorate inpatient readmission rates, VHA Handbook 1160.06, drafted in 2013, espouses the development and implementation of uniform recovery-oriented mental health (MH) services, which include treatment of SUDs addressing goals of recovery, improved quality of life, and community integration. The three types of treatments that will be evaluated are:

1. Combined Recovery Program (CRP), a six-session treatment group designed to explore goals, values, and personal strengths about making a change for overall quality of life, health and well-being combined with skill building designed for helping to live a more stable life in their own home that will include money management for financial success and home maintenance.
2. A Home Telehealth program, called Stable and Able (S\&A), designed to help maintain skills to stay sober and allows continued communication with one of the mental health staff on a daily basis to provide additional support for the next 3 months after discharge.
3. Treatment-as-usual (TAU), which is the treatment currently provided on the unit, consisting of various mental health topics and sessions designed to help with recovery.

All participant will receive TAU.

Objectives:

Specific Aim I: Assess the relative effects of Treatment Engagement and Substance Use \[and SUD-related problems\] between CRP+S\&A+TAU vs. CRP+TAU and CRP+S\&A+TAU vs. TAU only by 3-mos follow-up.

Primary Hypothesis 1a: Treatment Engagement: Participants in CRP + S\&A+TAU will attend more outpatient SUD treatment sessions and general MH treatment sessions compared to participants in CRP and to TAU.

Primary Hypothesis 1b: Substance Use: Participants in CRP + S\&A+TAU will lower quantity and frequency of substance use and SUD-related problems compared to participants in CRP+TAU and to TAU only.

Secondary Hypothesis 1c: Preventable Services: Participants in CRP + S\&A+TAU will reduce Preventable Healthcare Services (hospital readmissions and emergency department visits) compared to participants in CRP+TAU and to TAU only.

Secondary Hypothesis 1d: Participants in CRP + S\&A+TAU will report Greater QoL; # of Days Living in Stable Housing; and # of Days Engaging in Community Events and/or Activities compared to CRP+TAU and to TAU only.

Specific Aim II: Conduct Veteran participant and Staff thematic interviews and to assess qualitative facilitators and barriers to implementation.

Methods:

195 Veterans with SUDs admitted into the Charleston VAMC inpatient unit will be recruited. Participants will be randomly assigned to: (1) CRP + S\&A + TAU; (2) CRP+TAU; and (3) TAU. All participants will be followed-up at 1 and 3-months and data analyzed using mixed methods.

Conditions

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Alcoholism Substance-related Disorders Dual Diagnosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Between groups randomized controlled trial
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors
The PI and research staff providing follow up assessments will be blinded to participants study condition

Study Groups

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Combined Recovery Program (CRP)+Treatment-as-usual (TAU)

Combined Recovery Program (CRP) is a six-session motivational enhancement and daily living skills therapy workshop provided while on the inpatient unit. Attendance of CRP will be in addition to Treatment as Usual (TAU), that is, standard inpatient programming.

Group Type EXPERIMENTAL

Combined Recovery Program

Intervention Type BEHAVIORAL

A six-session treatment group designed to explore goals, values, and personal strengths about making a change for overall quality of life, health and well-being combined with skill building designed for helping to live a more stable life in their own home that will include money management for financial success and home maintenance.

CRP+ Stable & Able (S&A)+TAU

Combined Recovery Program (CRP) a six-session motivational enhancement and daily living skills therapy workshop provided while on the inpatient unit, plus a home telehealth program (Stable \& Able) which begins on day 1 of hospital discharge. Attendance of CRP and S\&A will be in addition to TAU, that is, standard inpatient programming.

Group Type ACTIVE_COMPARATOR

Combined Recovery Program

Intervention Type BEHAVIORAL

A six-session treatment group designed to explore goals, values, and personal strengths about making a change for overall quality of life, health and well-being combined with skill building designed for helping to live a more stable life in their own home that will include money management for financial success and home maintenance.

Stable & Able (S&A)

Intervention Type BEHAVIORAL

A 90-day Home Telehealth program designed to help maintain skills to stay sober.

Treatment-as-usual only (TAU):

TAU will only receive the usual care on the inpatient unit including medical and medication management.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Combined Recovery Program

A six-session treatment group designed to explore goals, values, and personal strengths about making a change for overall quality of life, health and well-being combined with skill building designed for helping to live a more stable life in their own home that will include money management for financial success and home maintenance.

Intervention Type BEHAVIORAL

Stable & Able (S&A)

A 90-day Home Telehealth program designed to help maintain skills to stay sober.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Meeting DSM-V criteria for current SUD diagnosis of alcohol and/or illicit drug use disorder
* Use of substances in past 30 days prior to date of index inpatient admission
* Able to comprehend English
* Able to provide informed consent
* Functioning at an intellectual level sufficient to allow accurate completion of all assessments
* Willing to commit to 6 group inpatient therapy sessions, telehealth S\&A, as well as baseline, and 1-and 3-month follow-up assessments

Exclusion Criteria

* Auditory or visual impairment that would interfere with study procedures
* Inability to speak or understand English
* Acutely psychotic patients
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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VA Office of Research and Development

FED

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Elizabeth J. Santa Ana, PhD MA BA

Role: PRINCIPAL_INVESTIGATOR

Ralph H. Johnson VA Medical Center, Charleston, SC

Locations

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Ralph H. Johnson VA Medical Center, Charleston, SC

Charleston, South Carolina, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Elizabeth J Santa Ana, PhD MA BA

Role: CONTACT

(843) 789-7168 ext. 7168

Facility Contacts

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Elizabeth J Santa Ana, PhD MA BA

Role: primary

843-789-7168 ext. 7168

Other Identifiers

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IIR 19-395

Identifier Type: -

Identifier Source: org_study_id

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