Efficacy of the Application of Xylocaine Impregnated Compress in Reducing Per-procedural Pain During Ultrasound-guided Infiltration of Trigger Finger

NCT ID: NCT05032508

Last Updated: 2022-11-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-06-07

Study Completion Date

2023-06-07

Brief Summary

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The purpose of this study is to assess the efficacy of Xylocaine impregnated compress in reducing per-procedural pain during ultrasound-guided infiltration of Trigger Finger

Detailed Description

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Trigger finger ultrasound-guided infiltrations are frequent and painful invasive procedures.

However, there is no current recommendation for per-procedural pain management, and in the majority of cases, infiltration is performed without prior skin anesthesia.

Xylocaine patches are of controversial efficacy in pain acute management. In current practice, they are not prescribed in advance and they are not well adapted to the topography of the finger.

On the other hand, a recent study showed the interest of administering lidocaine 2% by J-tip, a needle-free injection technique not available in France, before infiltration of Trigger Finger.

The investigators hypothesize that an impregnated compress in Xylocaine 20 mg/ml injectable solution, applied 15 minutes before the procedure, would reduce per-procedural pain.

Conditions

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Trigger Finger

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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xylocaine

Group Type EXPERIMENTAL

Lidocaïne Aguettant 20 mg/ml

Intervention Type DRUG

Lidocaïne Aguettant 20 mg/ml, injectable solution, applied to the skin with an impregnated compress, applied 15 minutes before infiltration performed by an experienced operator.

Placebo

Group Type PLACEBO_COMPARATOR

NaCl 0,9%

Intervention Type DRUG

Placebo (NaCl 0,9%), applied to the skin with an impregnated compress, applied 15 minutes before infiltration performed by an experienced operator.

Interventions

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Lidocaïne Aguettant 20 mg/ml

Lidocaïne Aguettant 20 mg/ml, injectable solution, applied to the skin with an impregnated compress, applied 15 minutes before infiltration performed by an experienced operator.

Intervention Type DRUG

NaCl 0,9%

Placebo (NaCl 0,9%), applied to the skin with an impregnated compress, applied 15 minutes before infiltration performed by an experienced operator.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 years or older
* Trigger Finger (clinically defined by painful difficulty or protrusion when extending the finger) with an ultrasound-guided infiltration of cortisone derivatives indication.
* Written consent
* Affiliation to a Social Security system
* Prior medical examination

Exclusion Criteria

* Neurological conditions affecting the hand other than carpal tunnel syndrome
* Intra-articular infiltration of the hand or the wrist ≤ 2 months
* Allergy to Xylocaine
* Contraindication to Xylocaine or cortisone derivatives
* Cognitive or behavioral disorders that make assessment impossible
* Persons referred to in articles L 1121-5; 6; 8; 9 of the Public Health Code (protected adults, under guardianship or curatorship, etc)
* Pregnancy and breastfeeding; absence of contraceptive method for women of childbearing age
* Participant unable to speak, read and write French
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondation de l'Avenir

OTHER

Sponsor Role collaborator

Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Henri GUERINI, MD

Role: PRINCIPAL_INVESTIGATOR

Assistance Publique - Hôpitaux de Paris

Locations

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Cochin hospital

Paris, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Henri GUERINI, MD

Role: CONTACT

+33 1 58 41 25 02

Laetitia PEAUDECERF, PhD

Role: CONTACT

+33 1 58 41 12 13

Facility Contacts

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Henri GUERINI, MD

Role: primary

+33 1 58 41 25 02

Christelle Nguyen, MD, PhD

Role: backup

+33 1 58 41 29 45

Other Identifiers

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2021-002052-36

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

APHP210094

Identifier Type: -

Identifier Source: org_study_id

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