Effect of Desflurane Versus Sevoflurane With Recent Bio-markers on Renal and Hepatic Functions
NCT ID: NCT05027191
Last Updated: 2021-08-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
70 participants
OBSERVATIONAL
2018-02-15
2019-12-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Sevoflurane
This group will receive sevoflurane as the maintenance inhalational anesthetic.
Neutrophil Gelatinase-Associated Lipocalin (NGAL)
The evaluation of inhalational anesthetics (desflurane and sevoflurane) on NGAL levels in laparoscopic cholecystectomy patients.
Sevoflurane
Sevoflurane
Desflurane
This group will receive desflurane as the maintenance inhalational anesthetic.
Neutrophil Gelatinase-Associated Lipocalin (NGAL)
The evaluation of inhalational anesthetics (desflurane and sevoflurane) on NGAL levels in laparoscopic cholecystectomy patients.
Desflurane
Desflurane
Interventions
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Neutrophil Gelatinase-Associated Lipocalin (NGAL)
The evaluation of inhalational anesthetics (desflurane and sevoflurane) on NGAL levels in laparoscopic cholecystectomy patients.
Desflurane
Desflurane
Sevoflurane
Sevoflurane
Eligibility Criteria
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Inclusion Criteria
2. Elective laparoscopic cholecystectomy.
3. Age: 25-55 years.
4. Gender: Both male and female.
5. Body Mass Index (BMI): 18.5-24.9 km2-(Normal weight).
Exclusion Criteria
2. Abnormal hepatic function by alanine aminotransferase (ALT) and aspartate aminotransferase (AST) values outside the normal range.
3. Abnormal renal function by blood urea nitrogen (BUN) and creatinine above the normal ranges.
4. Hypertension, unstable angina pectoris or myocardial infarction within the last six months.
5. Pregnancy and lactation.
6. Bronchial asthma.
7. Drug allergies.
8. Alcohol or drug addiction.
9. General anesthesia within the last three months.
25 Years
55 Years
ALL
No
Sponsors
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Cairo University
OTHER
Theodor Bilharz Research Institute
OTHER
Responsible Party
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khalda Galal Moustafa
Principal Investigator
Principal Investigators
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Khalda G Radwan, MD
Role: PRINCIPAL_INVESTIGATOR
Theodor Bilharz Rsearch Institute
Locations
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Theodor Bilharz Research Institute
Cairo, , Egypt
Countries
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Other Identifiers
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110-T
Identifier Type: -
Identifier Source: org_study_id
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