Remimazolam and Remifentanil Without Neuromuscular Blocking Agent

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

38 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-01

Study Completion Date

2022-01-31

Brief Summary

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Remimazolam is a novel drug approved for induction and maintenance of general anesthesia. This study aims to check the appropriate dose and patient response by administering remimazolam and remifentanil in surgery that does not require a neuromuscular blocking agents.

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Detailed Description

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Conditions

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Myoma;Uterus Polyp Endometrium Unspecified Condition Associated With Female Genital Organs and Menstrual Cycle

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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General anesthesia using remimazolam and remifentanil

Adult female patients scheduled for gynecological surgery under general anesthesia using remimazolam and remifentanil

Remimazolam

Intervention Type DRUG

Loading for anesthesia induction: Remimazolam 6 mg/kg/h until loss of consciousness Continuous infusion for anesthesia maintenance: Remimazolam 1-2 mg/kg/h under the Bispectral index monitoring

Interventions

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Remimazolam

Loading for anesthesia induction: Remimazolam 6 mg/kg/h until loss of consciousness Continuous infusion for anesthesia maintenance: Remimazolam 1-2 mg/kg/h under the Bispectral index monitoring

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Adult woman scheduled for gynecological surgery under general anesthesia
* American Society of Anesthesiology grade 1 or 2
* When using a laryngeal mask airway to maintain general anesthesia

Exclusion Criteria

* Underlying diseases: liver, kidney, brain nervous system, glaucoma
* Patients with BMI greater than 30 and less than 18.5
* Patients diagnosed with sleep apnea
* Alcohol or drug dependent patients
* Patients with severe or acute respiratory failure
* Lactose intolerance
* Dextran 40 hypersensitivity
* Patients in shock or coma

Minimum Eligible Age

20 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No