Effect of Transversus Abdominis Plane Block Combined With Dexmedetomidine Infusion on the Prognosis in Elderly Patients Undergoing Abdominal Surgery
NCT ID: NCT04516174
Last Updated: 2020-08-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
180 participants
INTERVENTIONAL
2020-09-01
2023-09-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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Dex+TAPB group
Patients in Dex+TAPB group will receive the bilateral transversus abdominis plane block with 0.25% ropivacaine 20ml each side before anesthesia and combined with continuous infusion of dexmedetomidine during operation.
Transversus abdominis plane block using ropivacaine
Before anesthesia, the ultrasound-guided bilateral transversus abdominis plane block using 0.25% ropivacaine was perdormed by anesthesiologist who is not involved in intraoperative management and postoperative follow-up and evaluate the effect after the block completed.
Dexmedetomidine
After finished the transversus abdominis plane block, then perform tracheal intubation and start the infusion of dexmedetomidine.
Control group
Patients in control group will receive the bilateral transversus abdominis plane block with saline 20ml each side before anesthesia and don't receive the infusion of dexmedetomidine during operation.
Transversus abdominis plane block using saline
Before anesthesia, the ultrasound-guided bilateral transversus abdominis plane block using saline was perdormed by anesthesiologist who is not involved in intraoperative management and postoperative follow-up and evaluate the effect after the block completed.
Saline
After finished the transversus abdominis plane block, then perform tracheal intubation and start the infusion of saline, dosage and infusion method of saline are consistent with dexmedetomidine.
Interventions
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Transversus abdominis plane block using ropivacaine
Before anesthesia, the ultrasound-guided bilateral transversus abdominis plane block using 0.25% ropivacaine was perdormed by anesthesiologist who is not involved in intraoperative management and postoperative follow-up and evaluate the effect after the block completed.
Dexmedetomidine
After finished the transversus abdominis plane block, then perform tracheal intubation and start the infusion of dexmedetomidine.
Transversus abdominis plane block using saline
Before anesthesia, the ultrasound-guided bilateral transversus abdominis plane block using saline was perdormed by anesthesiologist who is not involved in intraoperative management and postoperative follow-up and evaluate the effect after the block completed.
Saline
After finished the transversus abdominis plane block, then perform tracheal intubation and start the infusion of saline, dosage and infusion method of saline are consistent with dexmedetomidine.
Eligibility Criteria
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Inclusion Criteria
* American Society of Anesthesiologists physical status I-III
* Undergoing elective radical resection of colorectal cancer
* Sign informed consent
Exclusion Criteria
* Could not cooperate to complete the cognitive function assessment
65 Years
80 Years
ALL
No
Sponsors
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Beijing Tiantan Hospital
OTHER
Responsible Party
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Yuming Peng
Vice Professor
Locations
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Beijing Tian Tan Hospital
Beijing, , China
Countries
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Facility Contacts
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Other Identifiers
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wys20200731
Identifier Type: -
Identifier Source: org_study_id
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