Staging Classification of Severe Tricuspid Regurgitation Using Novel Cardiac Imaging Techniques

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-14

Study Completion Date

2025-04-30

Brief Summary

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The purpose of this research is to assess the severity of tricuspid regurgitation (a disorder in which the tricuspid valve in the heart does not close tight enough) using cardiac magnetic resonance imaging (MRI).

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Detailed Description

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40 patients with moderate or more TR on echocardiography will undergo CMR/MRE with contrast to assess TR severity, and the associated extra-valvular cardiac and liver abnormalities as shown in the flow diagram below. Patients will continue their clinical management by their primary physicians as per the standards of care. 1-year follow up will be conducted via phone to inquire about patient's vital status (dead/alive), symptoms and hospitalizations.

Conditions

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Tricuspid Regurgitation

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Moderate or severe tricuspid regurgitation

40 patients with moderate or more TR on echocardiography will undergo CMR/MRE with contrast to assess TR severity, and the associated extra-valvular cardiac and liver abnormalities. Patients will continue their clinical management by their primary physicians as per the standards of care. 1-year follow up will be conducted via phone to inquire about patient's vital status (dead/alive), symptoms and hospitalizations.

Group Type OTHER

Cardiac Magnetic Resonance

Intervention Type DIAGNOSTIC_TEST

a non-invasive assessment to determine severity of tricuspid regurgitation

Interventions

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Cardiac Magnetic Resonance

a non-invasive assessment to determine severity of tricuspid regurgitation

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Cardiac MRI

Eligibility Criteria

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Inclusion Criteria

* Moderate or more tricuspid regurgitation

Exclusion Criteria

1. Prior tricuspid valve prosthesis
2. Pacemaker/defibrillator that would impede MRI imaging
3. Planned tricuspid valve surgery
4. Primary liver pathology

Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No