The Effect of Beetroot Juice on Plasma Trimethylamine N-oxide Concentration
NCT ID: NCT05004935
Last Updated: 2023-11-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
20 participants
INTERVENTIONAL
2021-09-01
2023-12-15
Brief Summary
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A secondary aims: exploring the effect of circulating trimethylamine N-oxide modification on plasma total antioxidant status, and measurement of changes in the skin nicotinamide-adenine dinucleotide reduced form (NADH) content during transient ischemia and reperfusion.
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Detailed Description
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Plasma trimethylamine N-oxide, total antioxidant status, and nitrite/nitrate concentrations will be determined.
Using Flow Mediated Skin Fluorescence skin NADH content determined during controlled ischemia triggered by total occlusion of the brachial artery by the brachial blood pressure cuff and during reperfusion after deflation of the blood pressure cuff 2 and 4 hours following consumption.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
PREVENTION
NONE
Study Groups
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beetroot juice
single intake of beetroot juice containing 800mg nitrates
beetroot juice
single intake of beetroot juice containing 800mg nitrates
nitrates
single intake of 800mg nitrates (NaNO3)
nitrate
single intake of 800mg nitrates
Interventions
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beetroot juice
single intake of beetroot juice containing 800mg nitrates
nitrate
single intake of 800mg nitrates
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
18 Years
35 Years
ALL
Yes
Sponsors
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Poznan University of Physical Education
OTHER
Responsible Party
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Robert Olek
Principal Investigator
Principal Investigators
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Robert A Olek, PhD
Role: PRINCIPAL_INVESTIGATOR
Poznan University of Physical Education
Locations
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Akademia Wychowania Fizycznego
Poznan, , Poland
Countries
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References
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Jurga J, Samborowska E, Zielinski J, Olek RA. Effects of Acute Beetroot Juice and Sodium Nitrate on Selected Blood Metabolites and Response to Transient Ischemia: A Crossover Randomized Clinical Trial. J Nutr. 2024 Feb;154(2):491-497. doi: 10.1016/j.tjnut.2023.12.018. Epub 2023 Dec 16.
Other Identifiers
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RMPN2021/JJ
Identifier Type: -
Identifier Source: org_study_id
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