The Effect of Liposuction on Menses: a Retrospective Study

NCT ID: NCT04985591

Last Updated: 2021-08-02

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: EARLY_PHASE1
• Total Enrollment: 516 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-06-14
• Study Completion Date: 2021-03-12

Brief Summary

The prevalence of obesity nearly tripled from 1975 to 2021, resulting in liposuction, as an effective shaping method, to be performed more frequently. Liposuction is a surgical procedure that uses a specialized instrument to suck fat fragments in the subcutaneous fat layer through a small incision. Analyzing a large sample sizes of patients who had liposuction, we found that some female patients underwent menstrual irregularity after liposuction. In 2004, Carolyn et al. reported several cases in which there was a connection between liposuction and an early onset of menses. Further studies showed that an early onset of menses may be related to the volume of adipose tissue extracted, the amount of anesthesia given, the area of liposuction, and body weight. However, the sample of that study was small, as there were only 17 cases included in the statistical model, and there are few articles in which the impact of liposuction on menses has been studied. To better understand whether menstrual irregularity will occur after liposuction, patients with postmenopausal or preoperative menstrual irregularity were excluded, leaving a sample of 518 female patients to be reviewed. A better understanding of the impact of liposuction on menses may help clinical doctors predict the underlying risk of menstrual irregularity after liposuction and identify individuals at higher risk. The findings may contribute to further understanding of menstrual irregularity.

Conditions

Menstrual Irregularity

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

liposuction group

Group Type: EXPERIMENTAL

Liposuction

Intervention Type: PROCEDURE

A small, inconspicuous incision was made in the liposuction group to dislodge fat out of the body.

Other plastic surgery group

Group Type: PLACEBO_COMPARATOR

Other plastic surgery

Intervention Type: PROCEDURE

Other plastic surgery like blepharoplasty or keloid excision.

Interventions

Liposuction

A small, inconspicuous incision was made in the liposuction group to dislodge fat out of the body.

Intervention Type: PROCEDURE

Other plastic surgery

Other plastic surgery like blepharoplasty or keloid excision.

Intervention Type: PROCEDURE

Eligibility Criteria

Exclusion Criteria

-

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 55 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Shanghai Jiao Tong University School of Medicine

OTHER

Sponsor Role: lead

Responsible Party

Qing-FengLi Li,MD

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

SH9H-2019-T221-2

Identifier Type: -

Identifier Source: org_study_id