Impact of Weight Loss Surgery in Adolescents With NAFLD
NCT ID: NCT02952170
Last Updated: 2023-03-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
11 participants
INTERVENTIONAL
2014-09-15
2022-04-30
Brief Summary
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Detailed Description
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This study will establish the impact of WLS on NAFLD in adolescents. Currently, it is assumed that adolescents with NAFLD diagnosed at the time of WLS have universal resolution of their disease with appropriate weight loss, and no further evaluation is conducted. Our group has shown that up to 40% of adolescents who undergo WLS have persistently abnormal aminotransferase levels, suggesting that many may have persistent NASH and are at risk of progressive liver disease. The study will elucidate the history of NAFLD following WLS. Such data have not been previously published and will represent a significant contribution to this field.
Conditions
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Study Design
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NA
SINGLE_GROUP
PREVENTION
NONE
Study Groups
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MRI for steatosis assessment
Abdominal MRI for assessment of hepatic steatosis
MRI
MRI to assess hepatic steatosis
Interventions
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MRI
MRI to assess hepatic steatosis
Eligibility Criteria
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Inclusion Criteria
* Meets institutional requirements for weight loss surgery
Exclusion Criteria
* Intolerance to MRI
* Weight \>435 lbs
15 Years
22 Years
ALL
No
Sponsors
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National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Massachusetts General Hospital
OTHER
Responsible Party
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Kathleen E Corey
Director - MGH Fatty Liver Clinic
Principal Investigators
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Kathleen Corey, MD
Role: PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital
Locations
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Massachusetts General Hospital
Boston, Massachusetts, United States
Countries
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Other Identifiers
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2014P001504
Identifier Type: -
Identifier Source: org_study_id
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