A Community-based Prospective Cohort Study on Metabolic Dysfunction-Associated Fatty Liver Disease in Older Adults: From Metabolic Trajectories to Extrahepatic Outcomes

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

20000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-03-12

Study Completion Date

2030-12-31

Brief Summary

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To establish a cohort of elderly fatty liver disease based on the community medical examination population. Through the large-scale cohort study, the risk factors affecting fatty liver in the elderly will be explored in depth from the aspects of lifestyle, environment and genetics, the development pattern and mechanism of fatty liver in the elderly will be analysed, and the health risk assessment system and Chinese standard for fatty liver in the elderly covering cardiovascular risk, risk of hepatic fibrosis and risk of sarcopenia will be established, so as to provide the scientific basis for the precise intervention of fatty liver in the elderly in China.

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Detailed Description

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Conditions

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NAFLD and NASH NAFLD( Non-alcoholic Fatty Liver Disease ) NAFLD Cirrhosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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control group

No interventions assigned to this group

Observation Group

Lifestyle interventions

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* ① Elderly people aged ≥65 years among permanent residents (living for more than 5 years) in the survey area;

* Imaging diagnosis (ultrasound or FibroScan/FibroTouch) of fatty liver; -③ Voluntary participation in this study and signing an informed consent form.

Exclusion Criteria

* ①Major disability, mental illness, major wasting disease, severe cardiac, pulmonary and renal insufficiency;

* Patients with combined primary liver cancer or other types of cancer; -③Patients who have received liver transplant or other organ transplants.

Minimum Eligible Age

65 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes