Serum Adiponectin as an Early Marker for Renal Impairment in Patients With Non-alcoholic Fatty Liver Disease.

NCT ID: NCT05106049

Last Updated: 2021-11-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-12-31

Study Completion Date

2023-01-31

Brief Summary

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Early detection of renal impairment in patients with non-alcoholic fatty liver disease and its correlation with serum Adiponectin level.

Detailed Description

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Detection of serum Adiponectin by ELISA technique using (EIA-3418) KIT, DRG international inc., USA

Conditions

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Non-Alcoholic Fatty Liver Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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cases

non-alcoholic fatty liver patients

serum Adiponectin

Intervention Type DIAGNOSTIC_TEST

serum adiponectin as early marker for renal impairment. Adiponectin is a recently identified adipose tissue-derived protein (adipocytokine) with important metabolic ,antiinflammatory, anti-atherogenic, and reactive oxygen species protective actions.

control

healthy persons

serum Adiponectin

Intervention Type DIAGNOSTIC_TEST

serum adiponectin as early marker for renal impairment. Adiponectin is a recently identified adipose tissue-derived protein (adipocytokine) with important metabolic ,antiinflammatory, anti-atherogenic, and reactive oxygen species protective actions.

Interventions

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serum Adiponectin

serum adiponectin as early marker for renal impairment. Adiponectin is a recently identified adipose tissue-derived protein (adipocytokine) with important metabolic ,antiinflammatory, anti-atherogenic, and reactive oxygen species protective actions.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients with fatty liver aged from 18 to 60 yrs either diabetic or not .
* Patient with normal echogenic kidney in ultrasound and eGFR more than 60 mL/min/1.73m2.
* The Control group are completely healthy subjects without any systemic or liver and kidney affection

Exclusion Criteria

* Patients less than 18 yrs \& more than 60 yrs .
* All patients having any other causes of renal and hepatic disease rather than Diabetes and having any other systemic problem.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Hend Abdelrheem Ahmed

Hend Abdelrheem

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mohamed Hassan, Profissor.as

Role: STUDY_DIRECTOR

Assiut University

Central Contacts

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Hend Abdelrheem, Resident

Role: CONTACT

Phone: 01011062442

Email: [email protected]

References

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Stefan N, Stumvoll M. Adiponectin--its role in metabolism and beyond. Horm Metab Res. 2002 Sep;34(9):469-74. doi: 10.1055/s-2002-34785.

Reference Type RESULT
PMID: 12384822 (View on PubMed)

Other Identifiers

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Adiponectin in NAFLD

Identifier Type: -

Identifier Source: org_study_id