Combined Intensive and Conventional Exercise on Nonalcoholic Fatty Liver Disease (NAFLD)
NCT ID: NCT01418027
Last Updated: 2014-09-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
220 participants
INTERVENTIONAL
2011-08-31
2013-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Intensive exercise
The subjects receive an intensive exercise for 6 months and a subsequent conventional exercise for another 6 months.
Intensive exercise
Subjects conduct an aerobic exercise at 65-80% maximum oxygen consumption for 30 minutes each day, five days a week, totally for 6 months.Subsequently, moderate physical activity(3.0-6.0 MET s) at 150 min/wk for 6 months.
Lifestyle counseling
Subjects receive a general lifestyle counseling for 12 months
No interventions assigned to this group
Regular exercise
Subjects receive conventional exercise for 12 months
Conventional exercise
Subjects receive moderate physical activity(3.0-6.0 MET s) at 150 min/wk(30 min per day, five days a week) for 12 months.
Interventions
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Intensive exercise
Subjects conduct an aerobic exercise at 65-80% maximum oxygen consumption for 30 minutes each day, five days a week, totally for 6 months.Subsequently, moderate physical activity(3.0-6.0 MET s) at 150 min/wk for 6 months.
Conventional exercise
Subjects receive moderate physical activity(3.0-6.0 MET s) at 150 min/wk(30 min per day, five days a week) for 12 months.
Eligibility Criteria
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Inclusion Criteria
2. Age 40-65 years old;
3. Waist circumference\> 90cm for men and \> 85cm for women.
40 Years
65 Years
ALL
No
Sponsors
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Shanghai Jiao Tong University School of Medicine
OTHER
Responsible Party
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Xiao-Ying Li
Professor
Principal Investigators
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Xiaoying Li, MD,PhD
Role: PRINCIPAL_INVESTIGATOR
Shanghai Jiao Tong University School of Medicine
Locations
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The First Hospital Affiliated to Xiamen University
Xiamen, , China
Countries
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References
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Zhang HJ, He J, Pan LL, Ma ZM, Han CK, Chen CS, Chen Z, Han HW, Chen S, Sun Q, Zhang JF, Li ZB, Yang SY, Li XJ, Li XY. Effects of Moderate and Vigorous Exercise on Nonalcoholic Fatty Liver Disease: A Randomized Clinical Trial. JAMA Intern Med. 2016 Aug 1;176(8):1074-82. doi: 10.1001/jamainternmed.2016.3202.
Other Identifiers
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CCEMD011
Identifier Type: -
Identifier Source: org_study_id
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