Patogenic Mutation in 5 Genes

NCT ID: NCT04976439

Last Updated: 2021-07-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

22 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-05-01

Study Completion Date

2021-06-14

Brief Summary

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This is a pathogenic mutation profile of colorectal patients specifically in 5 genes, i.e. APC, TP53, PIK3CA, KRAS, and MLH1. Single nucleotide variants identified were synchronized with patients' characteristics.

Detailed Description

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Conditions

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Colorectal Cancer APC Gene Mutation TP53 Gene Mutation PIK3CA Gene Mutation KRAS Mutation-Related Tumors MLH1 Gene Mutation

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Age

co-occuring mutation

Intervention Type OTHER

APC, TP53, PIK3CA, KRAS APC, TP53, PIK3CA, MLH1 APC, TP53, PIK3CA, KRAS, and MLH1 APC, TP53, PIK3CA

Grade

co-occuring mutation

Intervention Type OTHER

APC, TP53, PIK3CA, KRAS APC, TP53, PIK3CA, MLH1 APC, TP53, PIK3CA, KRAS, and MLH1 APC, TP53, PIK3CA

Tumor location

co-occuring mutation

Intervention Type OTHER

APC, TP53, PIK3CA, KRAS APC, TP53, PIK3CA, MLH1 APC, TP53, PIK3CA, KRAS, and MLH1 APC, TP53, PIK3CA

Stage

co-occuring mutation

Intervention Type OTHER

APC, TP53, PIK3CA, KRAS APC, TP53, PIK3CA, MLH1 APC, TP53, PIK3CA, KRAS, and MLH1 APC, TP53, PIK3CA

Lymphovascular invasion

co-occuring mutation

Intervention Type OTHER

APC, TP53, PIK3CA, KRAS APC, TP53, PIK3CA, MLH1 APC, TP53, PIK3CA, KRAS, and MLH1 APC, TP53, PIK3CA

Interventions

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co-occuring mutation

APC, TP53, PIK3CA, KRAS APC, TP53, PIK3CA, MLH1 APC, TP53, PIK3CA, KRAS, and MLH1 APC, TP53, PIK3CA

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* FFPE samples fullfilling purity criterion and pass quality control

Exclusion Criteria

* none
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dr Cipto Mangunkusumo General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Vania Myralda Giamour Marbun

Principal Investigator - Staff of Digestive Division - General Surgery Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Vania Myralda Giamour Marbun

Jakarta, ALL, Indonesia

Site Status

Countries

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Indonesia

Other Identifiers

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MUTASICRC

Identifier Type: -

Identifier Source: org_study_id

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