Outcomes of Neoadjuvant Therapy for Rectal Cancer in a Tertiary Asian Institute

NCT ID: NCT05607186

Last Updated: 2022-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

59 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-01-01

Study Completion Date

2019-12-31

Brief Summary

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This is a retrospective cohort study that aims to evaluate the correlation of magnetic resonance tumour regression grade (mrTRG) and pathological TRG (pTRG) of locally advanced rectal cancer after neoadjuvant long course chemoradiotherapy as well as the prognostic value of mrTRG on survival.

Detailed Description

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Conditions

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Rectal Cancer Oncology

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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neoadjuvant long course chemoradiotherapy

neoadjuvant long course chemoradiotherapy consist of radiosensitizing 5FU or capecitabine and 50.4 Gy in 28 fractions over 5 weeks

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Rectal cancer
* At least 1 high risk feature on MRI
* Undergo long course neoadjuvant chemoradiotherapy (LCCRT)

Exclusion Criteria

* metastatic disease
* Patients who undergo short course radiotherapy
* Patients without a repeat MRI after completion of LCCRT
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Singapore General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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2019/2342

Identifier Type: -

Identifier Source: org_study_id

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