Ultrasound Evaluation of Hamstring Tendon Regeneration After ACL Reconstruction and Its Influence
NCT ID: NCT04961736
Last Updated: 2021-07-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
110 participants
OBSERVATIONAL
2018-02-02
2022-12-31
Brief Summary
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To clarify the mechanism between the biomechanical status of knee joint and the change of gait touch information, and to provide scientific basis for quantifying and evaluating the biomechanical status of knee joint in dynamic load-bearing state.
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Detailed Description
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Methods: 55 healthy people and 55 male patients with ACL reconstruction were recruited. All completed the basic rehabilitation training under the guidance of the postoperative rehabilitation program. Using infrared motion capture system, three-dimensional force measuring platform, isokinetic muscle force testing system and ultrasound, the anterior cruciate ligament reconstruction patients were tested before operation, 2 weeks, 3 months, 6 months, 12 months after operation and 24 months after operation.
Outcome evaluation indicators and statistical methods: evaluation indicators: (1) three dimensional motion capture and analysis results: 1) peak ground reaction force; 2) three-dimensional angle and torque of hip, knee and ankle joints in different stages; (2) isokinetic muscle strength results: bilateral knee extension torque and knee flexion torque at different angles and angular velocities. (3)Ultrasound evaluation: the thickness, cross-sectional area and shear wave velocity of the semitendinosus were measured.
Statistical methods: ① repeated measurement analysis of variance (ANOVA) was used to test the effects of different time after operation on the three-dimensional gait characteristics, muscle strength and tendon regeneration characteristics. ② Independent sample t-test was used to test the three-dimensional characteristics, muscle strength and tendon condition of patients at different time points after operation. ③ The difference of three-dimensional gait characteristics, muscle strength and tendon between the healthy side and the affected side at different time points after operation were examined by paired sample t-test. ④ Bivariate correlation analysis was used to analyze whether the thickness, cross-sectional area, shear wave propagation velocity and postoperative time were related.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Anterior Cruciate Ligament injury and reconstruction group
According to the previous clinical diagnosis, volunteers who has never suffered the Anterior Cruciate Ligament injury.
no intervention
This is an observation study, with no intervention
normal control group
According to the previous clinical diagnosis, volunteers who has never suffered the lower extremity sports injuries.
no intervention
This is an observation study, with no intervention
Interventions
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no intervention
This is an observation study, with no intervention
Eligibility Criteria
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Inclusion Criteria
* Patients who have isolated ACL injury and receive ACL reconstruction surgery at Peking University Third Hospital.
* With isolated ACL injury (an ACL injury with no need for surgical repairs to other knee structures).
* All participants have no known disorders or diseases other than ACL rupture.
Exclusion Criteria
18 Years
35 Years
ALL
Yes
Sponsors
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Peking University Third Hospital
OTHER
Responsible Party
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Principal Investigators
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Hongshi Huang, Doctor
Role: STUDY_CHAIR
Peking University Third Hospital
Locations
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Peking University Third Hospital
Beijing, , China
Countries
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Other Identifiers
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OR005
Identifier Type: -
Identifier Source: org_study_id
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