The Biomechanical Mechanism for Gait and Plantar Pressure Changes After Posterior Cruciate Ligament Rupture and Reconstruction

NCT ID: NCT04464343

Last Updated: 2020-07-09

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 110 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2014-06-14
• Study Completion Date: 2018-11-30

Brief Summary

Investigating the biomechanics for the PCL ruptured or reconstructed patients during walking, jogging, cutting, jumping. To establish a knee joint biomechanical evaluation model to quantify and evaluate the plantar pressure information under dynamic load-bearing state after PCL fracture. Provide a precise basis for the biomechanical state of the knee, and establish a clinically practical automatic analysis of plantar pressure information and an expert diagnostic system.

Detailed Description

Background: The posterior cruciate ligament (PCL) is an essential structure in knee stabilization. Knee cartilage degeneration after a PCL injury has been reported in several studies. Understanding the changes in movement patterns of patients with PCL ruptures could help clinicians make specific treatment protocols to restore patients' sporting ability and prevent joint degeneration. However, the kinematics and kinetics of the lower limb in patients with PCL injuries are still not clear.

Methods: Three-dimensional gait analysis system, force plate, electromyography will be used for 55 healthy male participants (control group) and 55 male patients with isolated PCL-deficiency (PCL-d group) during walking, jogging, cutting, jumping. Repeated measurement two-factor analysis of variance will be performed to determine differences between involved and uninvolved legs in the PCL-d group and control group at different rehabilitation times (prior reconstruction surgery, 6 months, and 1-year post PCL reconstruction surgery). Three-dimensional gait analysis and computer-aided analysis technology of plantar pressure information were used to study the changes of PCL after fracture and reconstruction. Based on the plantar pressure information, the movement parameters, and individual attribute parameters, establish a knee joint biomechanical evaluation model to quantify and evaluate the plantar pressure information under dynamic load-bearing state after PCL fracture. Provide a precise basis for the biomechanical state of the knee, and establish a clinically practical automatic analysis of plantar pressure information and an expert diagnostic system.

Conditions

Posterior Cruciate Ligament Tear

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Posterior cruciate ligament injury group

According to the previous clinical diagnosis, volunteers who has never suffered the Posterior cruciate ligament injury.

no intervention

Intervention Type: OTHER

This is an observation study, with no intervention

normal control group

According to the previous clinical diagnosis, volunteers who has never suffered the lower extremity sports injuries.

no intervention

Intervention Type: OTHER

This is an observation study, with no intervention

Interventions

no intervention

This is an observation study, with no intervention

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• age of 18-45 years old
• Healthy volunteers: no history of neuro or musculoskeletal system injury that may affect the movements.

Exclusion Criteria

• additional knee ligament or meniscal damage
• severe damage to the ipsilateral hip, ankle joint, or contralateral lower limb (ligament ruptures or bone fractures)
• age >50 years (to avoid age-induced osteoarthritis interference)
• any cartilage injury grade >2 according to the Outerbridge classification
• Tegner score18 <3

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 45 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Peking University Third Hospital

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Hongshi Huang, Doctor

Role: STUDY_CHAIR

Peking University Third Hospital

Locations

Peking University Third Hospital

Beijing, , China

Countries

China

Other Identifiers

OR006

Identifier Type: -

Identifier Source: org_study_id