6Degrees VR System for Treatment of Phantom Limb Pain

NCT ID: NCT04955613

Last Updated: 2021-07-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

122 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-07-29

Study Completion Date

2022-08-01

Brief Summary

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The treatment system consists of two light-weight MyMove bands and virtual-reality gear. Built-in software allows tracking of performance in real-time, with feedback to both the patient and treating personnel.

MyMove is a wearable device that allows patients with loss of upper-limb function to operate computers, cellular phones, and similar devices. The technology is non-invasive and does not involve risk to the patient.

MyMove+ is a Physical Medicine and Rehabilitation software intended for use in upper extremity and full-body conventional rehabilitation by:

1. Tracking motion and movement kinematics.
2. Guiding patients in the performance of physical exercises according to the treating practitioner's guidelines.

MyMove+ software is not intended for use in diagnosis, treatment or decision-making, or as a stand-alone device.

Detailed Description

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A non-blinded controlled study of adults, ages 18-65, with unilateral, below-knee limb amputation.

All subjects will be initially evaluated by a single group of licensed physical- and occupational therapists. Following a structured introductory session, subjects will be assigned to MyMove devices and VR gear for a total of 10 sessions over a period of 5 weeks (15-20 minutes per session).

Conditions

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Pain, Phantom

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

A non-blinded controlled study of adults. Each patient admitted to the study will be randomly allocated to either the treatment or control group (provided standard care) in consecutive order.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Standard care

12 sessions in total: sessions 1: Meeting with a doctor and physical therapist. sessions 2-11:Mirror therapy (standard care) for a total of 10 sessions over a period of 5 weeks (15-20 minutes per session).

sessions 12: Meeting with a doctor and physical therapist.

Group Type ACTIVE_COMPARATOR

Mirror therapy

Intervention Type DEVICE

Mirror therapy or mirror visual feedback is a therapy for pain or disability that affects one side of the patient more than the other side

MyMove/VR system

sessions 1: Meeting with a doctor and physical therapist. sessions 2-11:MyMove devices and VR gear for a total of 10 sessions over a period of 5 weeks 15-20 minutes per session.

sessions 12: Meeting with a doctor and physical therapist.

Group Type ACTIVE_COMPARATOR

MyMove/VR system

Intervention Type DEVICE

The treatment system consists of two lightweight MyMove bands and Virtual-Reality (VR) gear. Proprietary software and content allow tracking of performance in real-time, with feedback to both the patient and treating - personnel.

MyMove is a wearable device that allows patients with loss of upper limb function to operate computers, cellular phones, and similar devices. The technology is non-invasive and does not involve risk to the patient.

Virtual-Reality (VR) gear is a wearable computer running within goggles that project content and allow for interaction using controllers.

Interventions

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MyMove/VR system

The treatment system consists of two lightweight MyMove bands and Virtual-Reality (VR) gear. Proprietary software and content allow tracking of performance in real-time, with feedback to both the patient and treating - personnel.

MyMove is a wearable device that allows patients with loss of upper limb function to operate computers, cellular phones, and similar devices. The technology is non-invasive and does not involve risk to the patient.

Virtual-Reality (VR) gear is a wearable computer running within goggles that project content and allow for interaction using controllers.

Intervention Type DEVICE

Mirror therapy

Mirror therapy or mirror visual feedback is a therapy for pain or disability that affects one side of the patient more than the other side

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Clearance by the treating physician.
* Unilateral below-knee amputation
* History of phantom-limb pain with an intensity of 5-or-greater (VAS scale)
* Pain is not responsive to conventional drugs or other standard treatment.
* Range of motion (knee) of 10-to-90 degrees.

Exclusion Criteria

* Bilateral amputation
* History of phantom-limb pain with an intensity of 4-or-less (VAS scale)
* No prior attempt at therapy
* Declined by patient
* Pregnancy or other limitation related to special health-care groups.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sheba Medical Center

OTHER_GOV

Sponsor Role collaborator

6Degrees LTD

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Sheba Medical Center'

Ramat Gan, , Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Miri Berger

Role: CONTACT

+9720522700352

Aryeh H Katz

Role: CONTACT

+9720547796910

Facility Contacts

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Israel Dudkevitch, Prof.

Role: primary

+9720586503077

Avi Avitan, Dr.

Role: backup

+9720586503077

References

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Hoffman HG, Boe DA, Rombokas E, Khadra C, LeMay S, Meyer WJ, Patterson S, Ballesteros A, Pitt SW. Virtual reality hand therapy: A new tool for nonopioid analgesia for acute procedural pain, hand rehabilitation, and VR embodiment therapy for phantom limb pain. J Hand Ther. 2020 Apr-Jun;33(2):254-262. doi: 10.1016/j.jht.2020.04.001. Epub 2020 May 30.

Reference Type BACKGROUND
PMID: 32482376 (View on PubMed)

Ziegler-Graham K, MacKenzie EJ, Ephraim PL, Travison TG, Brookmeyer R. Estimating the prevalence of limb loss in the United States: 2005 to 2050. Arch Phys Med Rehabil. 2008 Mar;89(3):422-9. doi: 10.1016/j.apmr.2007.11.005.

Reference Type BACKGROUND
PMID: 18295618 (View on PubMed)

Sherman RA, Sherman CJ, Parker L. Chronic phantom and stump pain among American veterans: results of a survey. Pain. 1984 Jan;18(1):83-95. doi: 10.1016/0304-3959(84)90128-3.

Reference Type BACKGROUND
PMID: 6709380 (View on PubMed)

McCormick Z, Chang-Chien G, Marshall B, Huang M, Harden RN. Phantom limb pain: a systematic neuroanatomical-based review of pharmacologic treatment. Pain Med. 2014 Feb;15(2):292-305. doi: 10.1111/pme.12283. Epub 2013 Nov 13.

Reference Type BACKGROUND
PMID: 24224475 (View on PubMed)

Ramachandran VS, Rogers-Ramachandran D. Synaesthesia in phantom limbs induced with mirrors. Proc Biol Sci. 1996 Apr 22;263(1369):377-86. doi: 10.1098/rspb.1996.0058.

Reference Type BACKGROUND
PMID: 8637922 (View on PubMed)

Weeks SR, Anderson-Barnes VC, Tsao JW. Phantom limb pain: theories and therapies. Neurologist. 2010 Sep;16(5):277-86. doi: 10.1097/NRL.0b013e3181edf128.

Reference Type BACKGROUND
PMID: 20827116 (View on PubMed)

Other Identifiers

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202016500

Identifier Type: -

Identifier Source: org_study_id

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