Patient-Reported Outcomes Among Women Wtih Gynecological Cancer (The CONNECT Study)

NCT ID: NCT04945187

Last Updated: 2023-01-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

130 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-17

Study Completion Date

2024-02-01

Brief Summary

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Systematic nurse-led consultations based on electronic patient-reported outcomes (ePRO) will be tested among women with ovarian - and endometrial cancer receiving first-line chemotherapy.

Detailed Description

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Women with ovarian- and endometrial cancer often experiences a high disease and treatment-related physical and psychological burden. Patient-reported outcomes (PRO) have the potential to improve patient-clinician communication, symptom management, involvement, and quality of life. Electronic patient-reported outcomes (ePRO) can facilitate appropriate and continuous symptom monitoring reported by the patients. Nurses are with their holistic approach and their specialized knowledge and experience in a prominent position to address and facilitate symptom-management in a multidisciplinary context.

The overall aim of this study is to develop a model of care for systematic nurse-led consultations based on ePRO facilitating symptom management and to investigate how these consultations can be a part of the multidisciplinary treatment regimen for women with ovarian- and endometrial cancer receiving chemotherapy.

Conditions

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Gynecologic Cancer Gynecologic Neoplasm Ovarian Cancer Endometrial Cancer

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SEQUENTIAL

A prospective, sequential cohort study with comparisons between non-equivalent groups.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Standard care

No intervention. This arm will continue standard clinical practice consisting of clinical assessment regarding side effects and management before each cycle of chemotherapy conducted by physicians.

Group Type NO_INTERVENTION

No interventions assigned to this group

Intervention group

Intervention: This arm will be assigned to the intervention which will be nurse-led consultations based on electronic patient-reported outcomes. The patients will report ePRO weekly during chemotherapy and the answers will be used proactively in the nurse-led consultations. Nurses will conduct the clinical assessment regarding side effects and management before each cycle of chemotherapy.

Group Type EXPERIMENTAL

Nurse-led consultations based on electronic patient-reported outcomes

Intervention Type OTHER

The patients will weekly answer electronic patient-reported outcomes during chemotherapy and the answers will be used proactive in nurse-led consultations.

Interventions

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Nurse-led consultations based on electronic patient-reported outcomes

The patients will weekly answer electronic patient-reported outcomes during chemotherapy and the answers will be used proactive in nurse-led consultations.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Women ≥ 18 years
* Newly diagnosis of ovarian- or endometrial cancer
* Scheduled to receive first-line standard chemotherapy
* Having an active email, internet access and a device
* Able to understand, read and speak Danish

Exclusion Criteria

* Severe cognitive impairments/psychiatric disorder
* Participating in other interventional clinical trials
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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The Novo Nordic Foundation

OTHER

Sponsor Role collaborator

Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Helle Pappot

Professor, Clinical Oncologist, Consultant, DMSc

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mille Christiansen

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Locations

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Copenhagen University Hospital, Rigshospitalet

Copenhagen, , Denmark

Site Status RECRUITING

Countries

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Denmark

Central Contacts

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Mille Christiansen

Role: CONTACT

+45 35456347

Karin Piil

Role: CONTACT

Facility Contacts

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Mille Christiansen

Role: primary

+4535456347

Other Identifiers

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Copenhagen University Hospital

Identifier Type: -

Identifier Source: org_study_id

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