Primary Cyto-reductive Surgery Vs Neo-adjuvant Chemotherapy (NAC) in Epithelial Ovarian Cancer
NCT ID: NCT04257786
Last Updated: 2020-02-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
80 participants
INTERVENTIONAL
2020-03-01
2022-04-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Group 1
1ry surgery
1ry cyto-reductive surgery
1ry surgery then chemotherapy
Group 2
Neoadjuvant Chemotherapy followed by surgery
Neoadjuvant chemotherapy followed by surgery
chemotherapy then surgery
Interventions
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1ry cyto-reductive surgery
1ry surgery then chemotherapy
Neoadjuvant chemotherapy followed by surgery
chemotherapy then surgery
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Age ≥ 18 years old
Advanced defined as (stage 2D or more ) by surgical staging.
Performance status (PS) according to Eastern Cooperative Oncology Group (ECOG) ≤ 2
Chemotherapy naïve
Informed consent
Exclusion Criteria
Patients with uncontrolled infection.
Patients with active bleeding or conditions associated with high risk of bleeding.
contraindications for surgery
contraindications To chemotherapy - bevacizumab
18 Years
80 Years
FEMALE
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Ali hussien ali sayed
Specialist
Locations
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Ali hussien Ali sayed
Asyut, , Egypt
Countries
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Central Contacts
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References
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Abutaleb H, Hussien A, Khalaf M, Badary DM, Ismail AM, Hassanein S, AlGizawy S, Moustafa SAM, Farghaly RMM, Abdel-Kawi AF. Primary Cytoreductive Surgery Versus Neoadjuvant Chemotherapy Followed by Surgery in Patients with Advanced Primary Epithelial Ovarian Cancer in Low Resources Setting: A Randomized Clinical Trial. J Obstet Gynaecol India. 2025 Jun;75(3):199-205. doi: 10.1007/s13224-024-02061-w. Epub 2024 Nov 6.
Other Identifiers
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epithelial ovarian cancer
Identifier Type: -
Identifier Source: org_study_id
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