Isometric Exercise for People With Raised Blood Pressure

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-01

Study Completion Date

2022-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

High blood pressure affects many people in the United Kingdom. People with raised blood pressure (140-159/90-99 mmHg) are recommended to make changes in their lifestyle (e.g. smoking/alcohol/diet/exercise) and/or medication in order to reduce their blood pressure. Current knowledge suggests that a particular type of exercise - isometric exercise - can lower blood pressure. Isometric exercise involves holding a fixed body position for a short period of time. As most of the information about the benefits of this type of exercise comes from laboratory-based studies, researchers want to find out if it is possible for GP practices to offer NHS patients with clinically high blood pressure an isometric exercise plan to do at home and how it might affect their blood pressure over 6 months. They will also find out the experiences of those doing this type of exercise and whether it can be done consistently at home over time.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Isometric Resistance Training and Dose-dependent Effects in Pre- and Hypertensive Adults

NCT07251920

Hypertension Blood Pressure, High

COMPLETED PHASE3

Feasibility and Acceptability of Isometric Exercise and Lifestyle Change for the Management of Hypertension

NCT07213479

Hypertension (HTN)

RECRUITING NA

Blood Pressure and Cardiac Autonomic Adaptations to Isometric Exercise Training

NCT05025202

Hypertension

COMPLETED NA

Isometric Resistance Exercise for Hypertension

NCT06510998

Hypertension

RECRUITING NA

Lowering Blood Pressure by Changing Lifestyle

NCT04505150

High Blood Pressure

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hypertension

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Multi-centre randomized controlled feasibility study

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control

To receive standard care lifestyle advice only

Group Type OTHER

Standard care lifestyle advice

Intervention Type BEHAVIORAL

Healthy lifestyle advice for hypertension, given by a healthcare professional.

Isometric Exercise

To receive standard care lifestyle advice plus 3 sessions of isometric exercise per week

Group Type EXPERIMENTAL

Isometric Exercise

Intervention Type OTHER

Prescribed 6 months of isometric exercise training (three sessions per week, comprised of 4 x 2-minute bouts with 2-minute recovery periods in-between).

Standard care lifestyle advice

Intervention Type BEHAVIORAL

Healthy lifestyle advice for hypertension, given by a healthcare professional.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Isometric Exercise

Prescribed 6 months of isometric exercise training (three sessions per week, comprised of 4 x 2-minute bouts with 2-minute recovery periods in-between).

Intervention Type OTHER

Standard care lifestyle advice

Healthy lifestyle advice for hypertension, given by a healthcare professional.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Aged 18 or over
* Clinic systolic BP 140-159 mmHg
* Able to provide informed consent

Exclusion Criteria

* Currently taking anti-hypertensive medication
* White coat hypertension, as evidenced by averaged home systolic BP \<135 mmHg
* Inability to undertake study intervention (isometric exercise)
* Previous history of any of the following:

* Diabetes mellitus (Type 1 or type 2)
* Ischaemic heart disease (myocardial infarction and/or coronary angina and/or coronary revascularization procedure)
* Moderate or severe stenotic or regurgitant heart valve disease
* Atrial or ventricular arrhythmia
* Stroke or transient ischaemic attack
* Aortic aneurysm and/or peripheral arterial disease
* Uncorrected congenital or inherited heart condition
* Estimated glomerular filtration rate \<45 ml/min (calculated using CKD-EPI or MDRD formulae, and taking most recent documented results)
* Documented left ventricular ejection fraction \<45% and/or left ventricular hypertrophy (by either echocardiography or standard ECG criteria e.g. Sokolow-Lyon)
* Documented urine albumin:creatinine ratio \>3.5 mg/mmol
* Inability to provide informed consent
* If female, pregnancy or currently breast feeding
* Enrolled in another Clinical Trial of an Interventional Medicinal Product or Medical Device or other interventional study
* Medical condition that, in the opinion of the investigator, would make the participant unsuitable for the study

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No