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Acute Effects of Handgrip on Blood Pressure in Hypertensive Adults

NCT ID: NCT04856553

Last Updated: 2021-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

11 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-01

Study Completion Date

2021-08-30

Brief Summary

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The effect of handgrip training on blood pressure reduction has been demonstrated in several studies. However, acutely, there is still divergence regarding the effects of isometric handgrip exercise on blood pressure responses, especially when it is performed at different times of the day. It is suggested that the magnitude of blood pressure reduction after a single exercise session is able to predict long-term blood pressure behavior. Thus, understanding the effects of isometric handgrip exercise, performed at different times of the day, on blood pressure in adult hypertensive individuals acutely may help to understand the effects of this type of exercise chronically.

Detailed Description

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Conditions

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Hypertension

Keywords

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Exercise Blood pressure Strength training Vascular function

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Handgrip exercise (afternoon)

The handgrip exercise session will be executed with four series (two in each arm) of two minutes of isometric contraction at 30% of maximum voluntary contraction, with a one-minute interval between series in the afternoon.

Group Type EXPERIMENTAL

Acute effects of handgrip exercise

Intervention Type OTHER

The participants will be randomized into three sessions, handgrip exercise in the morning, handgrip exercise in the afternoon, and control performed in the morning to analyze the acute effects of handgrip exercise on blood pressure and vascular function at different times of the day. After the morning sessions, ambulatory blood pressure will also be measured for 24 hours.

Handgrip exercise (morning)

The handgrip exercise session will be executed with four series (two in each arm) of two minutes of isometric contraction at 30% of maximum voluntary contraction, with a one-minute interval between series in the morning.

Group Type EXPERIMENTAL

Acute effects of handgrip exercise

Intervention Type OTHER

The participants will be randomized into three sessions, handgrip exercise in the morning, handgrip exercise in the afternoon, and control performed in the morning to analyze the acute effects of handgrip exercise on blood pressure and vascular function at different times of the day. After the morning sessions, ambulatory blood pressure will also be measured for 24 hours.

Control

In the control session, the participants will remain at rest for the same period of time as in the handgrip exercise protocol.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Acute effects of handgrip exercise

The participants will be randomized into three sessions, handgrip exercise in the morning, handgrip exercise in the afternoon, and control performed in the morning to analyze the acute effects of handgrip exercise on blood pressure and vascular function at different times of the day. After the morning sessions, ambulatory blood pressure will also be measured for 24 hours.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. diagnosis of hypertension controlled by up to three antihypertensive medications;
2. SBP levels ≤ 180 mmHg and/or DBP ≤110 mmHg;
3. no serious heart disease;
4. no upper limb musculoskeletal injury that prevents the handgrip.

Exclusion Criteria

1. diagnosis of other cardiovascular diseases or diabetes during the study;
2. change the class and/or dose of antihypertensive medication during the study;
3. worsening of the disease (BP \> 180 or use of four or more medications).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universidade Federal de Santa Catarina

OTHER

Sponsor Role lead

Responsible Party

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Aline Mendes Gerage

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Aline M. Gerage, Dr.

Role: PRINCIPAL_INVESTIGATOR

Universidade Federal de Santa Catarina

Locations

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Universidade Federal de Santa Catarina

Florianópolis, Santa Catarina, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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ACUTE HANDGRIP 2021

Identifier Type: -

Identifier Source: org_study_id