Level of Immunity, Neutralization of the COVID-19 Virus and Reinfections in Residents of 2 Migrant Workers' Residences

NCT ID: NCT04932837

Last Updated: 2021-06-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-14

Study Completion Date

2021-07-02

Brief Summary

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A previous seroprevalence survey showed very high seroprevalence levels among residents of the two among the residents of the two migrant workers' hostels surveyed, indicating a high level of circulation of the virus SARS-COV-2 during the 1st wave of COVID-19. The constitution of a cohort after the event would be an opportunity to obtain opportunity to obtain answers to crucial questions: duration of immunity, potential reinfections potential reinfections, potential re-clustering. Going back to check the serological status seems feasible, especiallyespecially in the Foyers de Travailleurs Migrants (high probability of finding the participants).

There is an obvious scientific interest around the duration of immunity and reinfections in a population highly exposed during the first wave. Several articles document the decline of IgG antibodies in the months following an infection, but very few infection, but very few evaluate the protective character in the medium term (\>=6 months), especially in asymptomatic individuals. We are also concerned about the circulation of We are also concerned about the circulation of new variants and the immunity acquired after infection in residents.

To date, no study on the duration of immunity has been conducted in migrant worker's residences.

Detailed Description

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Conditions

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SARS-COV-2

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

PROSPECTIVE

Study Groups

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migrant worker residents

The target population will be the 124 residents in the 2 migrant worker residences who were included in the previous seroprevalence study and those who arrived at the 2 residences since September 1st, 2020

Blood and Saliva collection

Intervention Type BIOLOGICAL

Serological, viral RNA and antigenic test

Interventions

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Blood and Saliva collection

Serological, viral RNA and antigenic test

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* All individuals who consented to participate in the 1st study and who consent to participate in this study
* All individuals 18 years of age or older not residing in the 2 MWRs in July 2020 and permanently living in the MWR since September 2020 who consent to participate in this study

Exclusion Criteria

* Unwillingness to provide informed consent
* Unwillingness to provide blood
* Contraindication to venepuncture
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Medecins Sans Frontieres, Netherlands

OTHER

Sponsor Role collaborator

Institut Pasteur

INDUSTRY

Sponsor Role collaborator

Agence Regionale de Sante d'Ile de France

OTHER_GOV

Sponsor Role collaborator

Epicentre

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Elisabeth POULET, MD

Role: PRINCIPAL_INVESTIGATOR

Epicentre

Locations

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Foyer de travailleurs migrants

Montreuil, Île-de-France Region, France

Site Status

Foyer de travailleurs migrants

Villemomble, Île-de-France Region, France

Site Status

Countries

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France

Other Identifiers

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811562

Identifier Type: -

Identifier Source: org_study_id

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