Sero-epidemiology of Priority Arboviruses in French Guiana

NCT ID: NCT03210363

Last Updated: 2020-09-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

2697 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-09

Study Completion Date

2020-06-30

Brief Summary

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Dengue is an important public health problem despite the efforts of local health authorities to mitigate the impact of epidemics and the epidemiology of dengue evolved from an endemo-epidemic to a hyper-endemic state. In late 2013, the first local transmission of chikungunya virus in the Americas was identified in Caribbean countries and territories including French Guiana. Rapidly, more than 16,000 suspected local Health authorities had reported cases. In May 2015, the Pan American Health Organization (PAHO) issued an alert regarding the first confirmed Zika virus infections in Brazil. The emergence of Zika virus in South America led to a rapid spread throughout South and Central America, reaching French Guiana in December 2015. With the increasing frequency of epidemics related to arbovirus and the resulting health, social, and economic impacts of dengue, the surveillance of arbovirus have become social, political, and public health challenges that require specific and non-available immune status information.

Detailed Description

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French Guiana is a 250,000 inhabitant's French overseas department located in South America, the epidemiology of arboviruses has recently evolved and marked by important outbreaks.

Dengue remains an important public health problem despite the efforts of local health authorities to mitigate the impact of epidemics and the epidemiology of dengue evolved from an endemo-epidemic to a hyper-endemic state. In late 2013, the first local transmission of chikungunya virus in the Americas was identified in Caribbean countries and territories including French Guiana. Rapidly, more than 16,000 suspected local Health authorities had reported cases. In May 2015, the Pan American Health Organization (PAHO) issued an alert regarding the first confirmed Zika virus infections in Brazil. The emergence of Zika virus in South America led to a rapid spread throughout South and Central America, reaching French Guiana in December 2015. With the increasing frequency of epidemics related to arbovirus and the resulting health, social, and economic impacts of dengue, the surveillance of arbovirus have become social, political, and public health challenges that require specific and non-available immune status information.

Conditions

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Arbovirus Infections

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Guiana population

Human Biological samples from Guiana population :

Two serum tubes of blood will be collected

Group Type EXPERIMENTAL

Human Biological samples

Intervention Type OTHER

Blood sample

Interventions

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Human Biological samples

Blood sample

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Guiana resident for at least 6 months and present during the entire study period
* Age between 2 and 75 years old

Exclusion Criteria

* Subject under guardianship or deprived of liberty by judicial decision
* Subject with any pathology or health problem not compatible with blood sampling
Minimum Eligible Age

2 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Institut Pasteur

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Claude Flamand

Role: PRINCIPAL_INVESTIGATOR

Institut Pasteur de la Guyane

Locations

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Institut Pasteur de la Guyane

Cayenne, , France

Site Status

Countries

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France

Other Identifiers

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2016-073

Identifier Type: -

Identifier Source: org_study_id

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