Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires
NCT ID: NCT01214876
Last Updated: 2011-03-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
500 participants
OBSERVATIONAL
2010-08-31
2011-03-31
Brief Summary
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For individuals who experience a clinical malaria attack or who are diagnosed with high density parasitaemia (≥15,000 parasites/µL) during cross-sectional surveys, a 5mL blood sample is obtained to determine the diversity of parasite antigens in the population in relation to antigen recognition in the cohort.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Children 1-5 years old
No interventions assigned to this group
Children 6-10 years old
No interventions assigned to this group
Adults 25 years and above
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* written informed consent must be given
* the individual must have been resident of the area since birth or for a minimum period of two years
* the individual must be willing to submit required information and to participate in repeated sampling (total blood volume \~2.5 mL over a period of 12 months)
* Absence of danger signs (as defined by WHO) or clinical features of AIDS. An HIV-test will be offered to all participants at enrolment and completion of the study.
Exclusion Criteria
* unwillingness to reside in the study area during the follow-up period
1 Year
ALL
Yes
Sponsors
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London School of Hygiene and Tropical Medicine
OTHER
Medical Biotech Laboratories
UNKNOWN
University Of Perugia
OTHER
Imperial College London
OTHER
Microtest Matrices Ltd
UNKNOWN
Radboud University Medical Center
OTHER
Responsible Party
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London School of Hygiene & Tropical Medicine
Locations
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Medical Biotech Laboratories
Kampala, , Uganda
Countries
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Other Identifiers
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FIGHTMAL
Identifier Type: -
Identifier Source: org_study_id
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