Retinal Microvasculature Before and After Silicone Oil by OCTA

NCT ID: NCT04928196

Last Updated: 2023-03-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-12

Study Completion Date

2022-10-15

Brief Summary

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Prospective study to assess the retinal microvasculature, optic nerve head vasculature and retinal sensitivity using OCTA and microperimetry before and after silicone oil removal.

Detailed Description

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Prospective study to assess the retinal microvasculature, optic nerve head vasculature and retinal sensitivity using OCTA and microperimetry before and after silicone oil removal.

The study includes 30 patients with silicone oil tamponade will be evaluated before and after silicone oil removal

Conditions

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Retinal Vascular

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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Microperimtery and optical coherence tomography angiography OCTA

observational: Investigations are done to assess the retinal microvasculature and function before and after silicone oil removal

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 30 eyes of 30 patients with silicone oil tamponade will be evaluated before and after silicone oil removal

Exclusion Criteria

* Proliferative diabetic retinopathy, recurrent detachment or macular hole
* Patients with chorioretinal degenerations involving the macula
* Secondary complications as cataract, silicone oil emulsification, or secondary glaucoma
* Media opacity hindering proper imaging
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Kasr El Aini Hospital

OTHER

Sponsor Role lead

Responsible Party

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Hebatalla Makled

Ophthalmology lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hebatalla S. Makled, MD

Role: PRINCIPAL_INVESTIGATOR

Kasr El Aini Hospital

Ghada A. Nassar, MD

Role: PRINCIPAL_INVESTIGATOR

Kasr El Aini Hospital

Maha M. Youssef, MD

Role: PRINCIPAL_INVESTIGATOR

Kasr El Aini Hospital

Lameece M. Hassan, MD

Role: PRINCIPAL_INVESTIGATOR

Kasr El Aini Hospital

Locations

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Cairo University teaching hospital

Cairo, , Egypt

Site Status

Countries

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Egypt

References

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Nassar GA, Makled HS, Youssef MM, Hassan LM. Functional and perfusion changes associated with silicone oil tamponade after macula-off rhegmatogenous retinal detachment surgery: an optical coherence tomography angiography/microperimetry study. Int Ophthalmol. 2024 Feb 22;44(1):107. doi: 10.1007/s10792-024-03037-5.

Reference Type DERIVED
PMID: 38386180 (View on PubMed)

Other Identifiers

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6-1-2021-1

Identifier Type: -

Identifier Source: org_study_id

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