Comparison of the Speed of Functional Recovery (Constant Score) Between Two Different Approaches of Humeral Nailing in Humeral Fractures: Through the Rotator Cuff or Through the Rotator Interval Split (HUNAAP)

NCT ID: NCT04917536

Last Updated: 2025-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-21

Study Completion Date

2025-11-20

Brief Summary

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The aim of the study is to show if there is any speed difference of functional recovery for people with humeral fracture, treated by an anterograde nail, which will be inserted through the rotator cuff (the common way) or through the rotator interval split.

The patients included in this study will be randomized to one of the two groups.

The recovery will be evaluated by the Constant score over time, for a year. The main hypothesis is the rotator interval split approach allows a faster functional recovery after humeral nailing, by avoiding opening the rotator cuff.

Detailed Description

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Humeral fractures are the third most common fractures over 65 years and represent 8% of all fractures. The anterograde nailing is known to be an efficient way to treat humeral upper extremity fractures and humeral diaphysis fractures. The main complications of this nailing are pain, shoulder stiffness, rotator cuff tendinitis and impingement.

Studies have proven these problems can be due to the entry portal of the nail. Indeed, it is inserted through the supra-spinatus tendon, which means an opening of the rotator cuff even if it is closed at the end of the procedure.

But the rotator interval split in the shoulder can allow to insert the nail through it without opening the cuff or damaging the cartilage. It is located between the anterior side of the supra-spinatus tendon and the posterior side of the long part of the biceps.

The aim of the study is to compare the speed of functional recovery according to the entry portal, which are through the rotator cuff or through the rotator interval split, in humeral fractures treated by anterograde nailing.

The cutaneo-muscular approach will be the same in both groups, namely a trans-deltoid approach.

People will be included in the study after an enlightened and signed consent, afterward they will be randomized to one of the two groups.

To evaluate the primary outcome, the Constant Score will be used to measure the kinetic of the recovery.

The secondary outcomes are residual pain (measured by the VAS an evaluation of complications and a radiological review (two different reviewers) to follow the healing and search any side effects, the sick leave and rehabilitation durations.

The patients need to be available for a one-year follow-up. Each assessment will be checked at 21 and 45 days, and at 3, 6 and 12 months after the surgery.

Conditions

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Humeral Upper Extremity Fracture Humeral Diaphysis Fracture

Keywords

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Speed of functional recovery Humeral fractures Anterograde nailing Rotator cuff split Prospective randomized study

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Approach through the rotator cuff or through the rotator cuff split
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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rotator cuff approach

the nail is inserted through the supra-spinatus tendon, which is closed at the end of the surgery

Group Type ACTIVE_COMPARATOR

Humeral neailling in humeral fractures

Intervention Type PROCEDURE

Humeral neailling in humeral fractures

rotator cuff split approach

the nail is inserted through the rotator cuff split, between the supra-spinatus tendon and the long part of the biceps

Group Type EXPERIMENTAL

Humeral neailling in humeral fractures

Intervention Type PROCEDURE

Humeral neailling in humeral fractures

Interventions

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Humeral neailling in humeral fractures

Humeral neailling in humeral fractures

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Be available for a one year follow-up
* Patients over 18 and under 70 years old
* Humeral diaphysis fracture or humeral upper extremity articular fracture (Neer 2,3 or 4), needing to be treated by anterograde nailing.
* No growth plates
* Patients covered by the French social security service
* Patients able to give their enlightened consent and to answer the questions asked for the trial

Exclusion Criteria

* Pregmant, breastfeeding or potentially pregmant woman
* Existing bone disease
* Polytrauma
* Other fractures on the same upper limb
* Pathologic fracture
* Medical history of surgery on the same shoulder
* Contra-indication to the surgery or the anesthesia
* Infection on the operating site
* Axillary nerve palsy
* Deltoid dysfunction
* Major disability
* Refusal of participation
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Clermont-Ferrand

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Guillaume Villatte

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Clermont-Ferrand

Locations

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CHU de Clermont-Ferrand

Clermont-Ferrand, , France

Site Status

Countries

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France

Other Identifiers

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2021-A00400-41

Identifier Type: OTHER

Identifier Source: secondary_id

RBHP 2021 VILLATTE

Identifier Type: -

Identifier Source: org_study_id