Fractures of the Humeral Shaft With Primary Radial Nerve Palsy

NCT ID: NCT03948542

Last Updated: 2019-05-17

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 50 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2014-01-01
• Study Completion Date: 2015-03-01

Brief Summary

This study addresses the question if patients with fractures of the humeral shaft and primary radial nerve palsy gain nerve recovery.

Additionally the influence of injury mechanism, fracture type, and treatment modality on nerve recovery should be evaluated.

Detailed Description

Adult fractures of the humeral shaft account for approximately 3% of all fractures; most can be treated nonoperatively. Due to the anatomy of the radial nerve and the entrapment between fragments in spiral fractures of the humerus, these injuries are associated with primary radial nerve palsy in up to 18%.

Therefore, the purpose of this study was to assess the influence of injury mechanism, fracture type, and type of surgical treatment on time to onset of nerve recovery and time to full nerve recovery in patients with humeral shaft fractures and concomitant primary radial nerve palsy.

A retrospective analysis of prospectively collected data for all patients treated with humeral shaft fracture and primary radial nerve palsy at an academic Level-I trauma center was performed. Between 1994 and 2013 a total of 615 patients with traumatic humeral shaft fractures were treated at the department. The dataset was examined for completeness and accuracy. Patients with an incomplete dataset, those with a pathologic or periprosthetic fracture, patients with non-surgical treatment, or who were younger than 18 years of age were excluded from this series. According to these criteria, a total of 50 patients with a humeral shaft fracture and primary radial nerve underwent surgical treatment

Conditions

Radial Nerve Palsy; Functional Outcome

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

Outcome

Nerve conduction studies (NCV) Functional assessment according to Daniels and Worthingham

Outcome

Intervention Type: OTHER

Nerve Recovery

• NCV
• Funcional assessment

Interventions

Outcome

Nerve Recovery

• NCV
• Funcional assessment

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• patients treated with humeral shaft fracture and primary radial nerve palsy between 1994 and 2013 at the Department of Trauma Surgery, Medical University of Vienna
• surgical treatment
• complete data sets
• minimum 18 years of age

Exclusion Criteria

• Patients with an incomplete dataset
• those with a pathologic or periprosthetic fracture
• patients with non-surgical treatment
• or who were younger than 18 years of age

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Medical University of Vienna

OTHER

Sponsor Role: lead

Responsible Party

Thomas Tiefenboeck, M.D., MSc

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

F.o.t.H. Version 1.0

Identifier Type: -

Identifier Source: org_study_id