Pericapsular Nerve Group (PENG) Block Versus Lumbar Erector Spinae Plane Block

NCT ID: NCT04899388

Last Updated: 2023-06-26

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE2
• Total Enrollment: 69 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-06-01
• Study Completion Date: 2022-02-20

Brief Summary

assess and compare the efficacy of pericapsular nerve group block wersus lumber erector spinae plane block in reducing postoperative pain within the first 24 hours after hip surgeries.

Detailed Description

after being informed about the study and potential risks. All patients giving written consent will be randomized by double blind manner into 3groups each one containing 23 patients ,PENG group (n =23 ): The patients will receive Pericapsular Nerve Group Block (PENG Block) before positioning for spinal anesthesia.

ESPS group E (n =23 ): The patients will receive Lumbar Erector Spinae Plane Block before positioning for spinal anesthesia.

Control group C(n =23 ): patients received spinal anesthesia without any block.

Conditions

Pericapsular Nerve Group Block (PENG Block); Lumbar Erector Spinae Plane Block

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

PENG

the patients lied in the supine position. The probe was originally placed in a transverse plane above the anterior superior iliac spine in the ipsilateral surgical site and then counterclockwise rotated about 45 degrees to line up with the pubic ramus. The iliopubic eminence, iliopsoas muscle and tendon, femoral artery, and pectineus muscle were all visible in this view. By an in-plane technique, from lateral to medial, a 22-gauge, 80-mm needle was placed in the musculofascial plane between both the psoas tendon anteriorly and the pubic ramus posteriorly .The local anesthetic medication was delivered after negative aspiration while looking out for proper fluid distribution for a total volume of 20 mL of Bupivacaine 0.25%

Group Type: ACTIVE_COMPARATOR

Pericapsular Nerve Block

Intervention Type: PROCEDURE

regional anaesthia

ESPB

TThe patient was positioned at the lateral decubitus posture in the ipsilateral surgical site. The convex USG transducer was moved from the midline to the side of the operation and positioned 4-6 cm lateral to the L3 spinous process in a longitudinal parasagittal plane. The needle was advanced using the in-plane superior-to-inferior approach. The needle was advanced with the tip introduced up to the plane anterior to the "erector spinae muscle" and the posterior surface of the L3 transverse process. 0.5-1 ml of normal saline was administered for hydrodissection and to ensure proper placement .If there was any resistance during administering local anesthesia, the needle was modified by drawing it back a few millimeters. the prepared local anesthetic solution 20 ml bupivacaine 0.25 % was delivered through the point between both the transverse process and the erector spinae muscle

Group Type: ACTIVE_COMPARATOR

Lumbar Erector Spinae Plane Block

Intervention Type: PROCEDURE

regional anaesthia

control

patients received spinal anesthesia without any block

Group Type: PLACEBO_COMPARATOR

Fentanyl

Intervention Type: DRUG

intavenous

Interventions

Pericapsular Nerve Block

regional anaesthia

Intervention Type: PROCEDURE

Lumbar Erector Spinae Plane Block

regional anaesthia

Intervention Type: PROCEDURE

Fentanyl

intavenous

Intervention Type: DRUG

Other Intervention Names

PENG; LESB

Eligibility Criteria

Inclusion Criteria

Aged 65 to 75 years old. American Society of anesthesiologists physical status II and III. Body mass index of 25 to 30 kg/m2.

Exclusion Criteria

Altered mental status. History of trauma or multiple fractures Uncontrolled hypertension and or diabetes. Coagulopathy. Preexisting advanced kidney, liver, or heart disease. Allergies or contraindications to the study drugs. Chronic use of opioids or corticosteroids.

• Minimum Eligible Age: 65 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Zagazig University

OTHER_GOV

Sponsor Role: lead

Responsible Party

Marwa Mohamed Medhat

lecture of anesthesia and surgical intensive care (Principal Investigator)

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Howida A kamal, M.D

Role: STUDY_DIRECTOR

zagazig U

Marwa m Medhat, M.D

Role: PRINCIPAL_INVESTIGATOR

zagazig U

Locations

Aculty of Medicine,Zagazig University

Zagazig, Sharqia Province, Egypt

Countries

Egypt

Other Identifiers

6818

Identifier Type: -

Identifier Source: org_study_id