The Analgesic Effect of Pericapsular Nerve Group Block With Lateral Femoral Cutaneous Nerve Block and Pericapsular Nerve Group Block With Supra-inguinal Fascia Iliaca Block in Hip Hemiarthroplasty

NCT ID: NCT06577103

Last Updated: 2025-05-02

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-01-02
• Study Completion Date: 2024-12-01

Brief Summary

The aim of this study is to investigate the efficiency of preoperative and post-operative analgesia by pericapsular nerve group block (PENG) block with supra-inguinal fascia iliaca block (SIFIC) block compared with PENG block with lateral femoral cutaneous nerve block (LFCN) block in ease of giving a sitting position for spinal anesthesia and reducing narcotic consumption during the first 24 hour post-operatively and functional recovary by using the Visual analogue scale (VAS) of pain.

Detailed Description

The established practice to decrease pain using opioids in hip fracture surgery may result in compromised outcomes in the frail and elderly population with nausea-vomiting, constipation, delirium and respiratory depression. This popularized the regional analgesic techniques in the surgical treatment of hip fractures. Femoral nerve (FN) and supra-inguinal fascia iliaca block (SIFIC) block are documented to provide good peri-operative analgesia with reduced need for opioids.

The latest pericapsular nerve group block (PENG) block, is an interfacial plane block targeting the articular branches of the femoral, obturator (ON) and accessory obturator nerves (AON) at the hip.

An ability to perform in supine positioning, which is especially important in patients with acute hip fractures or chronic pain is an indigenous advantage of PENG block. Due to the blockade of only sensory articular branches, substantial motor weakness is unexpected. But exclusive use of PENG block for analgesia in hip fracture patients is not sufficient as it doesn't involve the cutaneous pain-generating area supplied by the lateral femoral cutaneous nerve block (LFCN).

Conditions

Pericapsular Nerve Group Block; Lateral Femoral Cutaneous Nerve Block; Supra-inguinal Fascia Iliaca Block; Hip Hemiarthroplasty

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Pericapsular nerve group block (PENG) with supra-inguinal fascia iliaca block (SIFIC)

Patients will receive pericapsular nerve group (PENG) block with supra-inguinal fascia iliaca (SIFIC) block.

Group Type: EXPERIMENTAL

Pericapsular nerve group block (PENG) with supra-inguinal fascia iliaca block (SIFIC)

Intervention Type: OTHER

Patients will receive pericapsular nerve group (PENG) block with supra-inguinal fascia iliaca (SIFIC) block.

Pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve block (LFCN)

Patients will receive pericapsular nerve group (PENG) block with lateral femoral cutaneous nerve (LFCN) block.

Group Type: EXPERIMENTAL

Pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve block (LFCN)

Intervention Type: OTHER

Patients will receive pericapsular nerve group (PENG) block with lateral femoral cutaneous nerve (LFCN) block.

Interventions

Pericapsular nerve group block (PENG) with supra-inguinal fascia iliaca block (SIFIC)

Patients will receive pericapsular nerve group (PENG) block with supra-inguinal fascia iliaca (SIFIC) block.

Intervention Type: OTHER

Pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve block (LFCN)

Patients will receive pericapsular nerve group (PENG) block with lateral femoral cutaneous nerve (LFCN) block.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age 40-80 years.
• Sex: Both sexes.
• American Society of Anaesthesiologists (ASA) Physical Status Class I, II, and III.
• Scheduled for hip hemiarthroplasty under general anesthesia.

Exclusion Criteria

• Declining to give a written informed consent.
• History of allergy to the medications used in the study.
• Contraindications to regional anesthesia (including patient refusal, coagulopathy and local infection).
• Psychiatric disorders or narcotic abusers.
• Significant cognitive dysfunction.
• American Society of Anesthesiologists (ASA) Physical Status Class IV.
• Renal insufficiency (to avoid local anesthetic or nalbuphine metabolites adverse effect)
• Opioid abuser patients
• Pregnancy.

• Minimum Eligible Age: 40 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Ain Shams University

OTHER

Sponsor Role: lead

Responsible Party

Moussa Elsayed

Assistant Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Ain Shams University,Egypt

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Ain Shams University

Cairo, Cairo Governorate, Egypt

Countries

Egypt

Other Identifiers

FMASU MD345/2023

Identifier Type: -

Identifier Source: org_study_id