Dose-dependent Impact of Daytime Lighting on Evening Responses to Light

NCT ID: NCT04882280

Last Updated: 2022-03-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-07-31

Study Completion Date

2024-07-31

Brief Summary

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The purpose of this study is to systematically examine the impact of different intensities of daytime light and the subsequent impact that such exposure has on non-image forming responses to light in the evening.

Detailed Description

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Conditions

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Sleep

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Low room

Low intensity (80 lux) room light

Group Type EXPERIMENTAL

Light

Intervention Type BEHAVIORAL

10 hours of light exposure during the daytime, starting 2 hours after habitual wake time

Normal room

Normal intensity (150 lux) room light

Group Type EXPERIMENTAL

Light

Intervention Type BEHAVIORAL

10 hours of light exposure during the daytime, starting 2 hours after habitual wake time

Bright room

High intensity (500 lux) room light

Group Type EXPERIMENTAL

Light

Intervention Type BEHAVIORAL

10 hours of light exposure during the daytime, starting 2 hours after habitual wake time

Bright

Very high intensity (1000 lux) room light

Group Type EXPERIMENTAL

Light

Intervention Type BEHAVIORAL

10 hours of light exposure during the daytime, starting 2 hours after habitual wake time

Interventions

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Light

10 hours of light exposure during the daytime, starting 2 hours after habitual wake time

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. Aged 18-65
2. Good health
3. Male or female
4. Normal color vision

Exclusion Criteria

1. Sleep disorders
2. Extreme chronotypes
3. Routine smoker
4. Significant hearing loss
5. Depressed
6. Alcohol use disorder
7. Use of illegal drugs
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Palo Alto Veterans Institute for Research

OTHER

Sponsor Role lead

Responsible Party

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Jamie M. Zeitzer, Ph.D.

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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VA Palo Alto Health Care System

Palo Alto, California, United States

Site Status

Countries

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United States

Central Contacts

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Jamie Zeitzer, PhD

Role: CONTACT

6504935000

Other Identifiers

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Reverse DRC

Identifier Type: -

Identifier Source: org_study_id

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