Human Circadian Sensitivity to Very Short Light Pulses

NCT ID: NCT01330992

Last Updated: 2011-08-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

400 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-12-31

Study Completion Date

2011-08-31

Brief Summary

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The mammalian eye serves both visual and non-image-forming functions. New information about the non-image-forming anatomy and physiology of the eye has revealed effects of ocular light stimuli on human circadian rhythms, melatonin suppression, heart rate, pupillary reflexes, cognitive performance, alertness and sleep. The results of the proposed work can be used to make predictions about the effects of light, to make recommendations involving exposure to or avoidance of light, and to design environmental lighting, resulting in improved health and alertness and decreased errors and accidents.

Detailed Description

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Conditions

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Circadian Rhythm Disorders

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Ocular Light or Dark Exposure

Ocular Light or Dark Exposure

Group Type EXPERIMENTAL

Ocular light or darkness exposure

Intervention Type OTHER

Ocular light or darkness exposure

Interventions

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Ocular light or darkness exposure

Ocular light or darkness exposure

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy volunteers

Exclusion Criteria

* No medications
* No eye disease
* No sleep disorders
* No psychiatric disorders
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Brigham and Women's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Elizabeth B. Klerman

Associate Professor, Associate Physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Brigham and Women's Hospital

Boston, Massachusetts, United States

Site Status

Countries

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United States

Other Identifiers

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NIH-RC2-HL101340

Identifier Type: -

Identifier Source: org_study_id

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