Impact of Age and BMI on Liver Transplant Outcomes

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

700 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-07-01

Study Completion Date

2022-11-30

Brief Summary

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Prospectively enrolled retrospective chart review and Liver Transplant database review to determine the modifiable and nonmodifiable risk factors specifically relating to Living Donor Liver Transplants. To observe the impact of age and BMI on graft outcomes and whether they impact the intraoperative management, post-operative length of stay, and complications.

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Detailed Description

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There has been a great deal of research into the characteristics of the donor for organ transplant, with older donors and those with more comorbidities having worse function once the organ is implanted. There has not been a great deal of research in the United States about the recipient's characteristic including age and BMI and the effects on donor organ function. With increasingly expanded criteria for organ recipients especially in the field of living donor organs the investigators plan to show the impact of older age and increased BMI on newly transplanted organs.

Conditions

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Liver Transplant; Complications Perioperative/Postoperative Complications

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Living Donor Liver Transplant Recipient

Patients who have received a living donor liver transplant.

Living Donor

Intervention Type PROCEDURE

Living Donor Organ Transplant

Deceased Donor Liver Transplant Recipient

Patients who have received either a Deceased by Circulatory Death or Deceased by Brain Death Liver Transplant

Cadaveric

Intervention Type PROCEDURE

Cadaveric Organ Transplant

Interventions

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Cadaveric

Cadaveric Organ Transplant

Intervention Type PROCEDURE

Living Donor

Living Donor Organ Transplant

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All patients who received a liver transplant at UPMC- Montefiore Hospital Age\> 18

Exclusion Criteria

* Excludes Children (\<18 years old) as they do not receive their operation under the same protocols Lost to follow-up prior to 1 year Participation in alternate research protocol that significantly altered the care they received in the perioperative period that may make their inclusion skew results.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No