Prediction of 30-Day Readmission Using Machine Learning

NCT ID: NCT04849312

Last Updated: 2022-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-20

Study Completion Date

2022-12-01

Brief Summary

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This is a retrospective observational study drawing on data from the Brigham and Women's Home Hospital database. Sociodemographic and clinic data from a training cohort were used to train a machine learning algorithm to predict the likelihood of 30-day readmission throughout a patient's admission. This algorithm was then validated in a validation cohort.

Detailed Description

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Conditions

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Infection Heart Failure Chronic Obstructive Pulmonary Disease Asthma Gout Flare Chronic Kidney Diseases Hypertensive Urgency Atrial Fibrillation Rapid Anticoagulants; Increased

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Training

A subset of patients that are used to train the machine learning algorithm.

No interventions assigned to this group

Validation

A subset of patients that are "held back" and used to validate the algorithm's accuracy.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

Was a subject in the Brigham and Women's Home Hospital study and has a completed record in the study's database.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Biofourmis Inc.

INDUSTRY

Sponsor Role collaborator

Brigham and Women's Hospital

OTHER

Sponsor Role lead

Responsible Party

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David Levine

Attending Physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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David Levine, MD MPH MA

Role: PRINCIPAL_INVESTIGATOR

Associate Physician

Locations

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Brigham and Women's Hospital

Boston, Massachusetts, United States

Site Status

Brigham and Women's Faulkner Hospital

Boston, Massachusetts, United States

Site Status

Countries

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United States

Central Contacts

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David Levine, MD MPH MA

Role: CONTACT

617 732 7063

References

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Merrill RK, Ferrandino RM, Hoffman R, Shaffer GW, Ndu A. Machine Learning Accurately Predicts Short-Term Outcomes Following Open Reduction and Internal Fixation of Ankle Fractures. J Foot Ankle Surg. 2019 May;58(3):410-416. doi: 10.1053/j.jfas.2018.09.004. Epub 2019 Feb 23.

Reference Type BACKGROUND
PMID: 30803914 (View on PubMed)

Li Q, Yao X, Echevin D. How Good Is Machine Learning in Predicting All-Cause 30-Day Hospital Readmission? Evidence From Administrative Data. Value Health. 2020 Oct;23(10):1307-1315. doi: 10.1016/j.jval.2020.06.009. Epub 2020 Sep 7.

Reference Type BACKGROUND
PMID: 33032774 (View on PubMed)

Xue Y, Klabjan D, Luo Y. Predicting ICU readmission using grouped physiological and medication trends. Artif Intell Med. 2019 Apr;95:27-37. doi: 10.1016/j.artmed.2018.08.004. Epub 2018 Sep 10.

Reference Type BACKGROUND
PMID: 30213670 (View on PubMed)

Morel D, Yu KC, Liu-Ferrara A, Caceres-Suriel AJ, Kurtz SG, Tabak YP. Predicting hospital readmission in patients with mental or substance use disorders: A machine learning approach. Int J Med Inform. 2020 Jul;139:104136. doi: 10.1016/j.ijmedinf.2020.104136. Epub 2020 Apr 18.

Reference Type BACKGROUND
PMID: 32353752 (View on PubMed)

Loreto M, Lisboa T, Moreira VP. Early prediction of ICU readmissions using classification algorithms. Comput Biol Med. 2020 Mar;118:103636. doi: 10.1016/j.compbiomed.2020.103636. Epub 2020 Feb 1.

Reference Type BACKGROUND
PMID: 32174313 (View on PubMed)

Bolourani S, Tayebi MA, Diao L, Wang P, Patel V, Manetta F, Lee PC. Using machine learning to predict early readmission following esophagectomy. J Thorac Cardiovasc Surg. 2021 Jun;161(6):1926-1939.e8. doi: 10.1016/j.jtcvs.2020.04.172. Epub 2020 May 29.

Reference Type BACKGROUND
PMID: 32711985 (View on PubMed)

Arvind V, London DA, Cirino C, Keswani A, Cagle PJ. Comparison of machine learning techniques to predict unplanned readmission following total shoulder arthroplasty. J Shoulder Elbow Surg. 2021 Feb;30(2):e50-e59. doi: 10.1016/j.jse.2020.05.013. Epub 2020 Jun 9.

Reference Type BACKGROUND
PMID: 32868011 (View on PubMed)

Other Identifiers

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2017P002583a

Identifier Type: -

Identifier Source: org_study_id

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