Prediction of Expected Length of Hospital Stay Using Machine Learning

NCT ID: NCT04784351

Last Updated: 2021-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-20

Study Completion Date

2021-12-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This is a retrospective observational study drawing on data from the Brigham and Women's Home Hospital database. Sociodemographic and clinic data from a training cohort were used to train a machine learning algorithm to predict length of stay throughout a patient's admission. This algorithm was then validated in a validation cohort.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Infection Heart Failure Chronic Obstructive Pulmonary Disease Asthma Gout Flare Chronic Kidney Diseases Hypertensive Urgency Atrial Fibrillation Rapid Anticoagulants; Increased

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Training

A subset of patients that are used to train the machine learning algorithm.

No interventions assigned to this group

Validation

A subset of patients that are "held back" and used to validate the algorithm's accuracy.

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Was a subject in the Brigham and Women's Home Hospital study and has a completed record in the study's database.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Biofourmis Inc.

INDUSTRY

Sponsor Role collaborator

Brigham and Women's Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

David Levine

Attending Physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

David Levine, MD MPH MA

Role: PRINCIPAL_INVESTIGATOR

Associate Physician

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Brigham and Women's Hospital

Boston, Massachusetts, United States

Site Status

Brigham and Women's Faulkner Hospital

Boston, Massachusetts, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

References

Explore related publications, articles, or registry entries linked to this study.

Lubelski D, Ehresman J, Feghali J, Tanenbaum J, Bydon A, Theodore N, Witham T, Sciubba DM. Prediction calculator for nonroutine discharge and length of stay after spine surgery. Spine J. 2020 Jul;20(7):1154-1158. doi: 10.1016/j.spinee.2020.02.022. Epub 2020 Mar 13.

Reference Type BACKGROUND
PMID: 32179154 (View on PubMed)

Karnuta JM, Churchill JL, Haeberle HS, Nwachukwu BU, Taylor SA, Ricchetti ET, Ramkumar PN. The value of artificial neural networks for predicting length of stay, discharge disposition, and inpatient costs after anatomic and reverse shoulder arthroplasty. J Shoulder Elbow Surg. 2020 Nov;29(11):2385-2394. doi: 10.1016/j.jse.2020.04.009. Epub 2020 Jun 9.

Reference Type BACKGROUND
PMID: 32713541 (View on PubMed)

Ramkumar PN, Navarro SM, Haeberle HS, Karnuta JM, Mont MA, Iannotti JP, Patterson BM, Krebs VE. Development and Validation of a Machine Learning Algorithm After Primary Total Hip Arthroplasty: Applications to Length of Stay and Payment Models. J Arthroplasty. 2019 Apr;34(4):632-637. doi: 10.1016/j.arth.2018.12.030. Epub 2018 Dec 27.

Reference Type BACKGROUND
PMID: 30665831 (View on PubMed)

Ma X, Si Y, Wang Z, Wang Y. Length of stay prediction for ICU patients using individualized single classification algorithm. Comput Methods Programs Biomed. 2020 Apr;186:105224. doi: 10.1016/j.cmpb.2019.105224. Epub 2019 Nov 20.

Reference Type BACKGROUND
PMID: 31765937 (View on PubMed)

Daghistani TA, Elshawi R, Sakr S, Ahmed AM, Al-Thwayee A, Al-Mallah MH. Predictors of in-hospital length of stay among cardiac patients: A machine learning approach. Int J Cardiol. 2019 Aug 1;288:140-147. doi: 10.1016/j.ijcard.2019.01.046. Epub 2019 Jan 19.

Reference Type BACKGROUND
PMID: 30685103 (View on PubMed)

Bacchi S, Oakden-Rayner L, Menon DK, Jannes J, Kleinig T, Koblar S. Stroke prognostication for discharge planning with machine learning: A derivation study. J Clin Neurosci. 2020 Sep;79:100-103. doi: 10.1016/j.jocn.2020.07.046. Epub 2020 Aug 5.

Reference Type BACKGROUND
PMID: 33070874 (View on PubMed)

Navarro SM, Wang EY, Haeberle HS, Mont MA, Krebs VE, Patterson BM, Ramkumar PN. Machine Learning and Primary Total Knee Arthroplasty: Patient Forecasting for a Patient-Specific Payment Model. J Arthroplasty. 2018 Dec;33(12):3617-3623. doi: 10.1016/j.arth.2018.08.028. Epub 2018 Sep 5.

Reference Type BACKGROUND
PMID: 30243882 (View on PubMed)

Young AJ, Hare A, Subramanian M, Weaver JL, Kaufman E, Sims C. Using Machine Learning to Make Predictions in Patients Who Fall. J Surg Res. 2021 Jan;257:118-127. doi: 10.1016/j.jss.2020.07.047. Epub 2020 Aug 18.

Reference Type BACKGROUND
PMID: 32823009 (View on PubMed)

Sinha I, Aluthge DP, Chen ES, Sarkar IN, Ahn SH. Machine Learning Offers Exciting Potential for Predicting Postprocedural Outcomes: A Framework for Developing Random Forest Models in IR. J Vasc Interv Radiol. 2020 Jun;31(6):1018-1024.e4. doi: 10.1016/j.jvir.2019.11.030. Epub 2020 May 4.

Reference Type BACKGROUND
PMID: 32376173 (View on PubMed)

Merrill RK, Ferrandino RM, Hoffman R, Shaffer GW, Ndu A. Machine Learning Accurately Predicts Short-Term Outcomes Following Open Reduction and Internal Fixation of Ankle Fractures. J Foot Ankle Surg. 2019 May;58(3):410-416. doi: 10.1053/j.jfas.2018.09.004. Epub 2019 Feb 23.

Reference Type BACKGROUND
PMID: 30803914 (View on PubMed)

Nemati M, Ansary J, Nemati N. Machine-Learning Approaches in COVID-19 Survival Analysis and Discharge-Time Likelihood Prediction Using Clinical Data. Patterns (N Y). 2020 Aug 14;1(5):100074. doi: 10.1016/j.patter.2020.100074. Epub 2020 Jul 4.

Reference Type BACKGROUND
PMID: 32835314 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2017P002583b

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.