Diagnoses Associated With Persistent Elevation of Creatine Kinase

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

148 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-05-01

Study Completion Date

2021-06-24

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Serum creatinine kinase (CK) level varies with age, gender, race and physical activity. For these reasons there is no normal serum CK level. Many pathological situations cause hyperCKemia, such as neuromuscular disorders (muscular dystrophy, inflammatory myositis, mitochondrial myopathy) and multiple systemic causes. The diagnostic approach to pauci or asymtomatic hyperCKemia can therefore be difficult and lead to multiple, and sometimes invasive tests, such as muscle biopsy. This study aims to describe the diagnoses associated with persistent elevation of serum creatine kinase and to precise the role of the muscule biopsy.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Roles of Uremic Toxins in Uremic Sacropenia

NCT03060590

Sarcopenia

COMPLETED

Determinants of Muscle Strength in Chronic Kidney Disease

NCT02806089

Chronic Kidney Disease

COMPLETED NA

Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease

NCT04330807

Chronic Kidney Disease Stage 3B Chronic Kidney Disease stage4 Chronic Kidney Disease Stage 5 +1 more

UNKNOWN NA

Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT

NCT05287204

Acute Kidney Injury Critical Illness Myopathy Dialysis; Complications

ACTIVE_NOT_RECRUITING

Skeletal Muscle Wasting and Renal Dysfunction After Critical Illness Trauma - Outcomes Study

NCT03736005

Critical Illness Acute Kidney Injury Muscle Loss +3 more

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Creatine Kinase Muscular Diseases

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Patients with elevated creatine kinase

no intervention

Intervention Type OTHER

retrospective descriptive without intervention

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

no intervention

retrospective descriptive without intervention

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patients hospitalised in a ward of internal medicin
* having a persistent elevation of serum creatine kinase \>3 times the upper normal laboratory value, repeated for 2 times

Exclusion Criteria

* known neuro-muscular disease causing elevation of creatine kinase
* evident post-traumatic cause responsible for the elevation of creatine kinase
* incomplete medical records

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No