Cannabinoides Concentrations and Hyperemesis Syndrom Occurrence in Regular Cannabis Consumer (CANEMESE)

NCT ID: NCT04836611

Last Updated: 2021-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-07-01

Study Completion Date

2023-06-30

Brief Summary

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The Cannabinoide Hyperemesis Syndrom (CHS) is defined as a recurrent syndrome of intractable vomiting that occurs in chronic cannabis consumers. The diagnosis is linked to clinical criteria only. The physiopathology of CHS is unknown and we observe an increase of cases with this syndrom since 2016 (Schreck et al., 2018).

The aim of this study is to investigate the involvement of exogenous cannabinoids concentrations in chronic cannabis users in the occurrence of CHS.

Detailed Description

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Conditions

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Chronic Consumption of Cannabis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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regular cannabis consumer patients

Group Type OTHER

1 blood sample

Intervention Type PROCEDURE

2 groups of subjects (group 1 : with diagnosis of CHS - group 2 : no diagnosis of CHS) will have 2 blood and 1 urine samples + 1 questionnaire

Interventions

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1 blood sample

2 groups of subjects (group 1 : with diagnosis of CHS - group 2 : no diagnosis of CHS) will have 2 blood and 1 urine samples + 1 questionnaire

Intervention Type PROCEDURE

Other Intervention Names

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1 urine sample

Eligibility Criteria

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Inclusion Criteria

* Subjects without protection by a legal regime (guardianship, trusteeship)
* Subjects affiliated to an appropriate social security system
* Subjects must sign an informed consent form


\- Subjects must have the CHS diagnosis confirmed


\- Subjects must be chronic cannabis consumers and never had CHS

Exclusion Criteria

* Subjects must not have addictive comorbidities or psychoactive substance abuse (except alcohol and tabacco)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Poitiers University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU

Poitiers, , France

Site Status RECRUITING

Countries

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France

Facility Contacts

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GUENEZAN Jérémy, MD

Role: primary

+33(0)549444444

Other Identifiers

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CANEMESE

Identifier Type: -

Identifier Source: org_study_id

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