New Psychoactive Substances in Intoxicated Patients During the Winter Activities

NCT ID: NCT04155281

Last Updated: 2023-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

87 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-23

Study Completion Date

2023-10-30

Brief Summary

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The purpose of this research is to identify the New Psychoactive Substances (NPS) that are responsible for intoxicating patients in ski resort during winter activities.

Detailed Description

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The New Psychoactive Substances expose to an additional risk of overdose or death due to their potency. These New Psychoactive Substances are used voluntarily by users wishing to test new substances, but also involuntarily because of association (unknowingly users) with more "conventional" drugs such as cocaine or heroin in the self-administered powder. These intoxications are still poorly known and the investigators believe that the identification of New Psychoactive Substances among the drugs consumed, and the association of their consumption with the appearance of a particular symptomatology allow the physician to guide the diagnosis and facilitate the care of future patients.

Conditions

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Acute Intoxication Psychoactive Substance Use

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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suspicion of intoxication

New Psychoactive Substances research in urine

urine analysis

Intervention Type OTHER

New Psychoactive Substances research in urine at admission in unit care

Interventions

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urine analysis

New Psychoactive Substances research in urine at admission in unit care

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Admission to emergency, resuscitation or intensive care departments involved in the study
* Anamnestic and / or clinical suspicion of acute drug poisoning according to International Classification of Diseases-10 criteria
* Patient coming from a ski resort from the pre-established list
* urine sample available as part of the treatment
* person understanding French or English
* Non-opposition to the study

Exclusion Criteria

* Suspicion of alcohol intoxication alone
* Suspicion of voluntary drug poisoning
* Suspicion of intentional intoxication by others
* Pregnant or breastfeeding women
* Major mentioned in Articles L1121-6 and 1121-8 of french public health code
* Patients in the exclusion period of another research involving the human person type 1 or 2
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Damien VIGLINO, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Grenoble

Locations

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Centre Hospitalier Métropole Savoie (Chaméry)

Chambéry, Savoie, France

Site Status

CH Albertville Moutiers

Albertville, , France

Site Status

University Hospital Grenoble

Grenoble, , France

Site Status

Countries

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France

References

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Fox J, Smith A, Yale A, Chow C, Alaswad E, Cushing T, Monte AA. Drugs of Abuse and Novel Psychoactive Substances at Outdoor Music Festivals in Colorado. Subst Use Misuse. 2018 Jun 7;53(7):1203-1211. doi: 10.1080/10826084.2017.1400067. Epub 2017 Nov 17.

Reference Type BACKGROUND
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Reference Type BACKGROUND
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Miliano C, Margiani G, Fattore L, De Luca MA. Sales and Advertising Channels of New Psychoactive Substances (NPS): Internet, Social Networks, and Smartphone Apps. Brain Sci. 2018 Jun 29;8(7):123. doi: 10.3390/brainsci8070123.

Reference Type BACKGROUND
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Reference Type BACKGROUND
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Helander A, Backberg M, Hulten P, Al-Saffar Y, Beck O. Detection of new psychoactive substance use among emergency room patients: results from the Swedish STRIDA project. Forensic Sci Int. 2014 Oct;243:23-9. doi: 10.1016/j.forsciint.2014.02.022. Epub 2014 Mar 6.

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Other Identifiers

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2019-A02214-53

Identifier Type: OTHER

Identifier Source: secondary_id

38RC19.214

Identifier Type: -

Identifier Source: org_study_id