Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
75 participants
INTERVENTIONAL
2021-03-22
2021-12-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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T-LAB / PRP KIT
In the first group, Platelet-rich plasma (PRP) prepared with T-LAB / PRP KIT injection in 3 sessions will be applied.
Intra-articular T-LAB / PRP KIT injection
Intra-articular 3 ml T-LAB / PRP KIT injection in 3 sessions will be applied. As a home exercise program, hamstring and quadriceps stretching, quadriceps isometric strengthening, short arc terminal extension exercises will be given at least three days a week with 3 sets of 10 repetitions.
T-LAB / PRP INJECTION SYRINGE
In the first group, Platelet-rich plasma (PRP) prepared with T-LAB / PRP INJECTION SYRINGE injection in 3 sessions will be applied.
Intra-articular T-LAB / PRP INJECTION SYRINGE injection
Intra-articular 3 ml T-LAB / PRP INJECTION SYRINGE injection in 3 sessions will be applied. As a home exercise program, hamstring and quadriceps stretching, quadriceps isometric strengthening, short arc terminal extension exercises will be given at least three days a week with 3 sets of 10 repetitions.
SALINE
In the first group, Platelet-rich plasma (PRP) prepared with SALINE injection in 3 sessions will be applied.
Intra-articular SALINE injection
Intra-articular 3 ml SALINE injection in 3 sessions will be applied. As a home exercise program, hamstring and quadriceps stretching, quadriceps isometric strengthening, short arc terminal extension exercises will be given at least three days a week with 3 sets of 10 repetitions.
Interventions
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Intra-articular T-LAB / PRP KIT injection
Intra-articular 3 ml T-LAB / PRP KIT injection in 3 sessions will be applied. As a home exercise program, hamstring and quadriceps stretching, quadriceps isometric strengthening, short arc terminal extension exercises will be given at least three days a week with 3 sets of 10 repetitions.
Intra-articular T-LAB / PRP INJECTION SYRINGE injection
Intra-articular 3 ml T-LAB / PRP INJECTION SYRINGE injection in 3 sessions will be applied. As a home exercise program, hamstring and quadriceps stretching, quadriceps isometric strengthening, short arc terminal extension exercises will be given at least three days a week with 3 sets of 10 repetitions.
Intra-articular SALINE injection
Intra-articular 3 ml SALINE injection in 3 sessions will be applied. As a home exercise program, hamstring and quadriceps stretching, quadriceps isometric strengthening, short arc terminal extension exercises will be given at least three days a week with 3 sets of 10 repetitions.
Eligibility Criteria
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Inclusion Criteria
* Presence of Kellgren-Lawrence stage 2-3 osteoarthritis on current anterior-posterior knee radiographs
* Functional ambulation scale stage 4-5
Exclusion Criteria
* History of severe trauma to the knee within the past six months
* Concomitant severe meniscus or ligament injury, surgery applied to the knee area
* Presence of severe effusion, inflammatory joint disease, infection, hematological and oncological disease in the knee.
* Having a bleeding disorder and / or using warfarin
* Kellgren-Lawrence stage 1 or stage 4 osteoarthritis on current anterior-posterior knee radiographs
* Presence of cardiac or systemic disease that may affect exercise
* The presence of neurological disease and psychiatric disease such as Parkinson's disease, stroke history that may affect balance
* Body Mass Index ≥35 kg / m²
30 Years
75 Years
ALL
No
Sponsors
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Istanbul University
OTHER
Responsible Party
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Sinan GOK
MD, Sub-Investigator
Principal Investigators
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Demirhan Diracoglu, Prof.
Role: STUDY_DIRECTOR
Istanbul University Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation
Ekin I Sen, Asst. Prof.
Role: PRINCIPAL_INVESTIGATOR
Istanbul University Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation
Locations
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Istanbul University Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation
Istanbul, Fatıh, Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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Istanbul Universty PRP
Identifier Type: -
Identifier Source: org_study_id
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