Temperature of Extremities and Necrotizing Enterocolitis

NCT ID: NCT04801537

Last Updated: 2022-10-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2024-12-31

Brief Summary

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Bloody stool and necrotizing enterocolitis(NEC) is two main focus in non-neonatal intensive care unit ward and usually lead to longed duration of hospitalization.

Neutral temperature is a environmental temperature where the infant's body temperature is normal under resting state, and the changes of body temperature and skin temperature are less than 0.2-0.3 centigrade. According the definition, a suggested temperature range is set. For example, if an infant's body weight is more than 2500 gram, the initial set of environmental temperature is 31.3 centigrade with a range of 29.8-32.8 centigrade.

low environmental temperature is a risk factor for Bloody stool and NEC. Therefore, how to set the optimal environmental temperature is a challenge.

Detailed Description

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After birth, newborns must adapt to their relatively cold environment by the metabolic production of heat because they are not able to generate an adequate shivering response. Under the condition, environment temperature should be given to protect an infant from cold stress and cold injury, even NEC.

Therefore, the setting of the optimal environment temperature is a key focus in neonatal ward. Here, the investigators suggest a hypothesis that environment temperature should be set to keep warmth of extremities temperature and infant's body temperature is between 36.7-37.3 centigrade.

In the present study, the investigators will test the hypothesis.

Conditions

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Neutral Temperature Bloody Stool Necrotizing Enterocolitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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normal body temperature and warm extremities

standard set of environmental temperature is done, and the infant's body temperature is normal and extremities are warm

normal body temperature and warm extremities

Intervention Type OTHER

environmental temperature is set according to the standard method to keep normal body temperature and warm extremities

normal body temperature and cold extremities

standard set of environmental temperature is done, and infant's body temperature is normal and extremities are cold

normal body temperature and cold extremities

Intervention Type OTHER

environmental temperature is set according to the standard method to keep normal body temperature, but cold extremities

Interventions

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normal body temperature and warm extremities

environmental temperature is set according to the standard method to keep normal body temperature and warm extremities

Intervention Type OTHER

normal body temperature and cold extremities

environmental temperature is set according to the standard method to keep normal body temperature, but cold extremities

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* body weight \>2500 grams and/or gestational age \>35 weeks
* an infant is diagnosed with hyperbilirubinemia and/or pneumonia without need for oxygen inhalation

Exclusion Criteria

* congenital deformities
* refusal of parents' consent
Minimum Eligible Age

1 Hour

Maximum Eligible Age

28 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Children's Hospital of Chongqing Medical University

OTHER

Sponsor Role collaborator

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

OTHER

Sponsor Role lead

Responsible Party

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Chen Long,MD

director

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Chen

Chongqing, Chongqing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Chen Long, MD, PhD

Role: CONTACT

+8613883559467

Facility Contacts

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Chen Long, MD,PhD

Role: primary

+8613883559467

Other Identifiers

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neutral temperature

Identifier Type: -

Identifier Source: org_study_id

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