Association Between Body Mass Index and HFNC Therapy Success

NCT ID: NCT04799132

Last Updated: 2021-03-16

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 303 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-03-11
• Study Completion Date: 2021-03-01

Brief Summary

Patients over 18 years of age who are admitted to the Intermediate Care Unit of the Clinica del Country and the Clinica la Colina, with symptoms suggestive of severe pneumonia secondary to COVID-19 infection and acute hypoxemic respiratory failure. The primary outcome will be to determine the relationship between body mass index and high-flow cannula therapy success defined as: No need for mechanical ventilation.

Detailed Description

All adult patients over 18 years of age admitted to the intermediate care service of the participating center with suspected SARS-CoV-2 pneumonia will be considered as potential candidates for the study.

The medical records of patients in our cohort who require high-flow cannula therapy and who met all the inclusion criteria and none of the exclusion criteria will be reviewed.All data will be processed and analyzed using the SPSS 26 software once the study is completed. study sample

Conditions

Covid19; Obesity; Overweight; Pneumonia, Viral

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Eligibility Criteria

Inclusion Criteria

1. Patients over 18 years of age.

2. Diagnosis of severe pneumonia secondary to COVID-19 infection and acute respiratory distress syndrome, defined by upper and lower respiratory symptoms plus positive C-reactive protein test for COVID-19.

3. Patient admission to the Clinical del Country and Clinica de la Colina intermediate care units.

4. Oxygen therapy by high-flow system (high-flow cannula) requirement.

5. Anthropometric data availability upon admission to our facilities.

Exclusion Criteria

1. Patients with a survival expectancy of less than 12 months according to the Charlson scale categorization or patients with oncological pathology.

2. Patients under 18 years of age.

3. Pregnant women.

4. Patients with cardiogenic pulmonary edema.

5. History of chronic liver disease or cirrhosis Child - Pugh C.

6. Patients with contraindications to high-flow cannula therapy initiation.

7. Patients with respiratory, hemodynamic and neurological indications that contraindicate HFNC initiation.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Clínica del country

OTHER

Sponsor Role: lead

Responsible Party

Carlos Augusto Celemín Florez, MD.

Principal Investigator.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Clínica del Country.

Bogotá, , Colombia

Countries

Colombia

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Other Identifiers

BMI AND HFNC

Identifier Type: -

Identifier Source: org_study_id