Quality of Life After Hysterectomy (AdenoQOL)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

218 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-18

Study Completion Date

2030-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Adenomyosis is a disease where ectopic endometrial-like glands affect the muscular wall of the uterus. About 70% of women affected by adenomyosis suffer from dysmenorrhea and menorrhagia. A levonorgestrel-releasing intrauterine device (LNG-IUD) is the first-choice treatment of adenomyosis, but is not always sufficiently effective in all women. Those women often end up removing the uterus (hysterectomy).

Hysterectomy is clinically regarded to be an efficient and final treatment of adenomyosis, but pelvic pain may also prevail after removal of the uterus. This study aimes to investigate the short - and long-term impact of hysterectomy on quality of life (QOL) and sexual function in women with adenomyosis, and further to evaluate if there is any difference compared to women that are removing their uterus due to other benign gynecological conditions.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Health-Related QoL Among Women Receiving Hysterectomy in NTUH

NCT00155870

Leiomyoma Adenomyosis

UNKNOWN

Radiofrequency Endometrial Ablation or Uterine Artery Embolization for Treatment of Adenomyosis-related Abnormal Uterine Bleeding

NCT07195305

Abnormal Uterine Bleeding Due to Adenomyosis (Disorder)

NOT_YET_RECRUITING NA

Robot-assisted Laparoscopic Hysterectomy-RALH- Postoperative Complications, Quality of Life and Health Economics

NCT01761721

Endometrial Cancer Treatment by Robotic Assisted Laparoscopy Hysterectomy

COMPLETED

Hysterectomy and Levonorgestrel Releasing Intrauterine System (LNG-IUS) in the Treatment of Menorrhagia

NCT00966264

Menorrhagia

COMPLETED PHASE3

Intrauterine Device Versus Uterine Artery Embolization for Adenomyosis

NCT06043583

Adenomyosis

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Adenomyosis Quality of Life

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Adenomyosis

Patients with adenomyosis

Hysterectomy

Intervention Type PROCEDURE

Elective procedure with hysterectomy due to benign gynecological condition

Other benign gynecological conditions

Patients with other benign gynecological conditions (i.e: myomas, endometriosis).

Hysterectomy

Intervention Type PROCEDURE

Elective procedure with hysterectomy due to benign gynecological condition

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Hysterectomy

Elective procedure with hysterectomy due to benign gynecological condition

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Premenopausal status defined by having had menstruation within the last 12 months, or age \< 50 years if amenorrhea due to hormonal treatment
* Hysterectomy planned due to a benign condition
* Able to communicate in Norwegian or English
* Electronic consent given

Exclusion Criteria

* Age \< 18 years, postmenopausal status or no menstrual bleeding for the last 12 months
* Hysterectomy as part of female-to-male transition
* Pelvic organ prolapse as an indication for hysterectomy
* Gynecological cancer suspected at the time of inclusion
* Not able to communicate in Norwegian or English

Minimum Eligible Age

18 Years

Maximum Eligible Age

52 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No