Role of the MSCT in Evaluation of the Congenital Cardiovascular Anomalies

NCT ID: NCT04787172

Last Updated: 2021-03-08

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 50 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-06-01
• Study Completion Date: 2022-09-01

Brief Summary

Congenital heart diseases (CHDs) are considered as the most common congenital birth defects, comprising 1% of all live births . Echocardiography remains a first-line non-invasive imaging tool for establishing the diagnosis and follow-up in most patients .This method is operator dependent and limited by an acoustic window .

Traditional angiography is typically utilized as the gold standard modality for diagnosing CHD, but it is an invasive method and need general anseathsia with dose of radiation exposure .After recent developments in CT and MR technologies, cardiac catheterization is no longer necessary for diagnosis .

Detailed Description

The interpretation of cardiovascular structures on cardiac CT scan studies is similar to that for echocardiography, however, it is not limited by the acoustic window or operator dependent like ultrasonography. In addition to the anatomic information, a cardiac CT scan provides hemodynamic information, including extracardiac and intra-cardiac shunts. It also enables the systematic evaluation of other thoracic structures like cardiovascular structures, the airways and the lungs by using maximum and minimum intensity projections to delineate the vascular and airway structures, respectively. Extra-cardiac great vessels can be evaluated along their length; thus augmenting the role of cardiac CT scans in children with congenital heart diseases .Inspite of the poorer temporal resolution of cardiac CTA compared to echocardiography, yet the combination of rapid acquisition time, increased anatomic coverage, high spatial resolution, multiplanar reformation and 3D capability combined with a flexible ECG synchronization have improved the image quality of cardiac CT scans and minimizing the patient risks. Multidetector computed tomography has greatly advanced the noninvasive diagnosis of these anomalies in pediatric patient, thus makes MDCT an ideal non- invasive method for evaluating pediatric patients .

Conditions

MSCT in Congenital Cardiovascular Disease

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Interventions

Multi Slice computed tomography

use of MSCT as a diagnostic tool in evaluation of patients with congenital cardiovascular anomalies

Intervention Type: RADIATION

Eligibility Criteria

Inclusion Criteria

• patients suffering from congenital cardiovascular diseases diagnosed either clinically or by echocardiographic examination.

Exclusion Criteria

• orthopenic patient patients with hypersensitivity to contrast , medium and poor renal function .

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Sara Ali Gamal

specialist

Responsibility Role: PRINCIPAL_INVESTIGATOR

Central Contacts

Sara Ali Gamal, MD

Role: CONTACT

sararad423@yahoo.com

01020230930

References

Goitein O, Salem Y, Jacobson J, Goitein D, Mishali D, Hamdan A, Kuperstein R, Di Segni E, Konen E. The role of cardiac computed tomography in infants with congenital heart disease. Isr Med Assoc J. 2014 Mar;16(3):147-52.

Reference Type: RESULT

PMID: 24761701 (View on PubMed)

Other Identifiers

MSCT in congenital CVA

Identifier Type: -

Identifier Source: org_study_id