Clinical Audit On Management Of Congenital Heart Disease In ACUH

NCT ID: NCT03850223

Last Updated: 2020-02-24

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 100 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-03-01
• Study Completion Date: 2021-12-01

Brief Summary

Congenital Heart Disease (CHD) is the most common birth defect in the United States, affecting approximately 0.8% of live births. Improved treatment strategies and interventions have increased survival such that 85% to 90% of affected children are expected to live well into adulthood, thereby causing a demographic shift in which adults now outnumber children with CHD, and more people with complex CHD are living longer.

Detailed Description

CHD may be defined as an anatomic malformation of the heart or great vessels which occurs during intrauterine development, irrespective of the age at presentation. The cause of most congenital heart defects is still unknown. Many cases of congenital heart disease are multifactorial and result from a combination of genetic predisposition and an environmental stimulus. A small percentage of congenital heart lesions are related to known chromosomal abnormalities, in particular, trisomy 21, 13, and 18 and Turner syndrome. Of all cases of congenital heart disease, 2-4% are associated with known environmental or adverse maternal conditions and teratogenic influences, including maternal diabetes mellitus, phenylketonuria, systemic lupus erythematosus or congenital rubella syndrome; and maternal ingestion of drugs (lithium, ethanol, warfarin, antimetabolites, vitamin A derivatives, anticonvulsant agents).

Conditions

Congenital Heart Disease

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• children with CHD more than one month

Exclusion Criteria

• children with CHD less than one month

• Minimum Eligible Age: 1 Month
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Fadwa Magdy Mohamed Abdou

Principle investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Central Contacts

Mostafa Shafeek Khalaf, Professor

Role: CONTACT

mostafa.tawfeek1@med.au.edu.eg

+201112110096

Khaled Abdelaziz Sanusy, Assistant Professor

Role: CONTACT

khalids@aun.edu.eg

+201003068421

Other Identifiers

MOCHD

Identifier Type: -

Identifier Source: org_study_id