Effects of Auditory Stimulation on Sleep and Memory in Schizophrenia
NCT ID: NCT04783571
Last Updated: 2025-01-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
70 participants
INTERVENTIONAL
2020-04-13
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
DOUBLE
Study Groups
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Schizophrenia
Adult outpatients with a diagnosis of schizophrenia.
Placebo
Auditory stimulation will not be delivered during the nap
Auditory Stimulation
Auditory stimulation will be delivered during the nap
Healthy Controls
Adult participants screened to exclude a personal history of mental illness, family history of schizophrenia spectrum disorder, and psychoactive medication use.
Placebo
Auditory stimulation will not be delivered during the nap
Auditory Stimulation
Auditory stimulation will be delivered during the nap
Interventions
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Placebo
Auditory stimulation will not be delivered during the nap
Auditory Stimulation
Auditory stimulation will be delivered during the nap
Eligibility Criteria
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Inclusion Criteria
* Male and female subjects
* 18-50 years of age
* Proficient in English
For schizophrenia patients:
* Male and female schizophrenia outpatients
* 18-50 years of age
* Proficient in English
* Able to give informed consent
Exclusion Criteria
* Current use of psychotropic medications (healthy controls only)
* A history of head injury resulting in prolonged loss of consciousness or other neurological sequelae
* IQ \<85
* Neurological disorder (including seizure disorder)
* Significant hearing or vision loss
* Current substance abuse or dependence (nicotine abuse or dependence is not exclusionary)
* Any unstable chronic medical condition that affects sleep
* Diagnosed sleep disorder
18 Years
50 Years
ALL
Yes
Sponsors
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Massachusetts General Hospital
OTHER
Responsible Party
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Dara S. Manoach, PhD
Professor
Principal Investigators
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Dara Manoach, PhD
Role: PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital
Locations
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Massachusetts General Hospital
Boston, Massachusetts, United States
Countries
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Other Identifiers
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2018P002573
Identifier Type: -
Identifier Source: org_study_id
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