Quorn in Community Health Experiment

NCT ID: NCT04773483

Last Updated: 2023-03-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

82 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-11-09

Study Completion Date

2021-12-17

Brief Summary

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In overweight individuals (BMI \> 27.5 kg/m2), does daily consumption of mycoprotein containing Quorn Food products lower blood cholesterol compared with daily meat/fish consumption?

Detailed Description

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Conditions

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Overweight and Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Quorn Food products

Group Type ACTIVE_COMPARATOR

Quorn Foods products

Intervention Type DIETARY_SUPPLEMENT

180 g mycoprotein (wet weight; corresponding to 45 g dry weight) per day (equates to approx. 215 g Quorn Foods products, depending on the product)

Meat/fish products

Group Type ACTIVE_COMPARATOR

Meat/fish products

Intervention Type DIETARY_SUPPLEMENT

Standard meat/fish products matched to Quorn group for protein intake

Interventions

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Quorn Foods products

180 g mycoprotein (wet weight; corresponding to 45 g dry weight) per day (equates to approx. 215 g Quorn Foods products, depending on the product)

Intervention Type DIETARY_SUPPLEMENT

Meat/fish products

Standard meat/fish products matched to Quorn group for protein intake

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* 18-70 years old
* BMI \>27.5 kg/m2
* Non allergic to penicillin/mycoprotein
* Moderate levels of physical activity or below (self-identified; NDNS servey)
* Omnivores
* Not currently using cholesterol lowering medication

Exclusion Criteria

* \<18 or \>70 years old
* BMI \<27.5 kg/m2
* Allergies to penicillin/mycoprotein
* Heavy exercisers (self idenfiied)
* Vegetarian/vegans
* Currently using cholesterol lowering medication
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Marlow Foods Ltd

UNKNOWN

Sponsor Role collaborator

NIHR Exeter Clinical Research Facility

NETWORK

Sponsor Role collaborator

University of Exeter

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Benjamin T Wall, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Exeter

Locations

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University of Exeter

Exeter, Devon, United Kingdom

Site Status

Countries

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United Kingdom

References

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Pavis GF, Iniesta RR, Roper H, Theobald HE, Derbyshire EJ, Finnigan TJA, Stephens FB, Wall BT. A four-week dietary intervention with mycoprotein-containing food products reduces serum cholesterol concentrations in community-dwelling, overweight adults: A randomised controlled trial. Clin Nutr. 2024 Mar;43(3):649-659. doi: 10.1016/j.clnu.2024.01.023. Epub 2024 Jan 24.

Reference Type DERIVED
PMID: 38306892 (View on PubMed)

Other Identifiers

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201021-B-02 Wall

Identifier Type: -

Identifier Source: org_study_id

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