Impact of "ASAP" Multidisciplinary Optimization Care Protocol on Clinical Outcome in Elderly Inpatients for Hip Fracture

NCT ID: NCT04771364

Last Updated: 2023-01-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2022-12-31

Brief Summary

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To compare the impact of ASAP protocol (geriatric advice, early surgery, loco-regional anesthesia and pharmacological adaptation) on elderly patients with hip fracture and clinical outcome.

Detailed Description

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Retrospective double cohort analysis for ASA physical status 1, 2 and 3 elderly patients \>65 years old, scheduled to undergo surgery for hip fracture between January 1st 2017 and December 31st 2022.

The investigator want to confirm the better outcome on 30-days mortality after surgery in patients where the ASAP protocol was applied, starting from 1 January 2020.

ASAP protocol follow the latest international guidelines about hip fracture in elderly patient. The investigator focuses the research about the impact of ASAP protocol on clinical outcome: geriatrician's advice, impact of loco-regional techniques on intra-operative and postoperative pain control, chronic pharmacological therapy's adaptation and 30-days postoperative mortality.

Conditions

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Hip Fractures

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Standard care

Patients aged \>65 years old scheduled for hip fracture between January 1st 2017 and December 31th 2019.

Standard anesthesiology cares were performed, as usual in our hospital institution.

No interventions assigned to this group

ASAP cohort

Patients aged \>65 years old scheduled for hip fracture between January 1st 2020 and December 31th 2022.

Standard anesthesiology cares were performed, as usual in our hospital institution, but the investigator focused the attention on these cares' adaptation: early geriatrician's advice, prefer locoregional anesthesia techniques where possible, early surgical therapy and medical adaptation on chronic therapy.

ASAP care's protocol

Intervention Type OTHER

Early geriatrician's advice, prefer locoregional anesthesia techniques where possible, early surgical therapy and medical adaptation on chronic patient's therapy (in particular with regard to sedative, anticholinergic and psychotropic drugs).

Interventions

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ASAP care's protocol

Early geriatrician's advice, prefer locoregional anesthesia techniques where possible, early surgical therapy and medical adaptation on chronic patient's therapy (in particular with regard to sedative, anticholinergic and psychotropic drugs).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Over 65 years old patients with hip fractures between January 1st 2017 and December 31th 2022

Exclusion Criteria

* Fracture without indication for surgery
* Death before surgery
* Intensive care's or polytrauma patients (\> 2 fracture sites) or under pharmacological coma needed before and after surgery.
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Liege

OTHER

Sponsor Role lead

Responsible Party

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Jean François Brichant

Head of Anesthesiology Departement

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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CHU de Liège

Liège, , Belgium

Site Status

Countries

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Belgium

References

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Borges FK, Bhandari M, Patel A, Avram V, Guerra-Farfan E, Sigamani A, Umer M, Tiboni M, Adili A, Neary J, Tandon V, Sancheti PK, Lawendy A, Jenkinson R, Ramokgopa M, Biccard BM, Szczeklik W, Wang CY, Landoni G, Forget P, Popova E, Wood G, Nabi Nur A, John B, Sleczka P, Feibel RJ, Balaguer-Castro M, Deheshi B, Winemaker M, de Beer J, Kolesar R, Teixidor-Serra J, Tomas-Hernandez J, McGillion M, Shanthanna H, Moppett I, Vincent J, Pettit S, Harvey V, Gauthier L, Alvarado K, Devereaux PJ. Rationale and design of the HIP fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) Trial: a protocol for an international randomised controlled trial evaluating early surgery for hip fracture patients. BMJ Open. 2019 May 1;9(4):e028537. doi: 10.1136/bmjopen-2018-028537.

Reference Type BACKGROUND
PMID: 31048449 (View on PubMed)

Matsuo M, Yamagami T, Higuchi A. Impact of age on postoperative complication rates among elderly patients with hip fracture: a retrospective matched study. J Anesth. 2018 Jun;32(3):452-456. doi: 10.1007/s00540-018-2494-8. Epub 2018 Apr 16.

Reference Type RESULT
PMID: 29663067 (View on PubMed)

Other Identifiers

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ASAP

Identifier Type: -

Identifier Source: org_study_id

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