MEP and Neuromuscular Blocker

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-09

Study Completion Date

2022-05-13

Brief Summary

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It is important to predict the influence of the neuromuscular blocking agents on the motor evoked potential. Investigator will investigate the dose-response relationship between the degree of the neuromuscular blockade and the motor evoked potential in patients undergoing brain tumor surgery using the population approach. Investigator will investigate the influence of the other factors such as the impedence, reactance, muscel amount, and age on the motor evoked potential.

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Detailed Description

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Conditions

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Brain Tumor

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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rocuronium

Neuromuscular blockade will be performed using rocuronium.

Group Type EXPERIMENTAL

Arm I (MEP)

Intervention Type DRUG

Arm I (MEP): Motor evoked potential will be measured in various degree of the neuromuscular blockade.

Interventions

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Arm I (MEP)

Arm I (MEP): Motor evoked potential will be measured in various degree of the neuromuscular blockade.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1\. Patients aged 19 years old or older, with American Society of Anesthesiologists Physical Status 1-3, and scheduled for elective brain tumor surgery under the monitoring of the motor evoked potential

Exclusion Criteria

1. Central or peripheral neuromuscular disease
2. Sensory or motor nerve disorder
3. Allergy to propofol, remifentanil, and rocuronium
4. Patients with pacemaker

Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No