Role of Parasitic Infection in Inflammatory Bowel Disease and Irritable Bowel Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-30

Study Completion Date

2024-06-30

Brief Summary

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Role of parasitic infection in Inflammatory bowel disease and Irritable bowel The burden of the parasitic disease is in-direct relation with the health and nutritional status of the host, inducing not only parasite-specific immunity but also can modify the host's immune responses . Many parasites can imitate inflammatory bowel disorders and some studies showed that infection with parasites can improve disorders like IBD or moderate the symptoms of inflammatory bowel disorders . Even though, many studies have shown that gastrointestinal infection is an important risk factor for the development of IBS

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Detailed Description

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1. Detect the prevalence of parasite/s associated with Inflammatory bowel diseases (IBD) and Irritable bowel syndrome (IBS) in comparison with control subjects.
2. Evaluating the effect of the parasite on the course and prognosis of the diseases.
3. Evaluating the effect of the antiparasitic drugs on the course and prognosis of the diseases.

Conditions

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Parasite IBS IBD

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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IBD GROUPS

PATIENT WITH IBD DISEASE

No interventions assigned to this group

IBS GROUP

PATIENT WIT IBS DISEASE

No interventions assigned to this group

CONTROL 1

CONTROL WITH POSITIVE PARASITIC INFECTION AN POSITIVE GIT SYMTOMS

No interventions assigned to this group

CONTROL2

HEALTHY VOLUNTEARS

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of IBD will be confirmed using

1. standard clinical,
2. endoscopic,
3. radiographic and4 pathological criteria according to the Montreal classification of the extent and severity of IBD
* Diagnosis of IBS will depend on Rome IV criteria

1. Recurrent abdominal pain on average at least 1 day/week in the last 3 months,
2. associated with two or more of the following criteria:
3. Related to defecation;
4. Associated with a change in the frequency of stool and/ or Associated with a change in the form (appearance) of stool.