Effects of High-intensity Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke.

NCT ID: NCT04752124

Last Updated: 2021-03-16

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2020-11-07
• Study Completion Date: 2021-03-15

Brief Summary

Stroke is one of the major cause of morbidity and mortality and the leading cause of disability in adults all around the world. Stroke survivors can suffer several neurological impairments and deficits which have an important impact on patient's quality of life and which increase the costs for health and social services. After stroke, impairments in ADLs and functional status, deterioration in health related quality of life can be seen.

The purpose of this study is to Determine the effect of high intensity speed based treadmill training on Balance, Walking capacity and quality of life in sub-acute stroke.

Conditions

Stroke

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

HIIT+CT

HIIT combined with conventional rehabilitation.

Group Type: ACTIVE_COMPARATOR

Exercise Therapy

Intervention Type: OTHER

High intensity speed based interval treadmill training

conventional therapy

Intervention Type: OTHER

conventional physical therapy

Conventional therapy

Conventional rehabilitation will be provided to this group of patients.

Group Type: PLACEBO_COMPARATOR

conventional therapy

Intervention Type: OTHER

conventional physical therapy

Interventions

Exercise Therapy

High intensity speed based interval treadmill training

Intervention Type: OTHER

conventional therapy

conventional physical therapy

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• age 40-80 years; first episode of stroke; >4 weeks of stroke onset; hemiparesis resulting from unilateral ischaemic stroke; Ashworth score of 0 or 1, indicating no spasticity or slight spasticity over the affected lower limb, respectively; mini-mental state examination score ≥23; ability to perform independent walking for at least five minutes with or without an assistive device (FAC=3). All patients will be determined to be in stable cardiovascular condition with a low although slightly greater risk for vigorous exercise than for apparently healthy persons (class B according to the American College of Sports Medicine [ACSM]).13

Exclusion Criteria

• Participants will be excluded from the study if they had any of the following: (1) chronic cardiorespiratory or metabolic diseases; (2) severe osteoporosis; and (3) lesions pertaining to the brainstem or cerebellum; (4) having resting blood pressure above 160/100 mmHg even after taking medications; (5) cardiovascular comorbidity (aortic stenosis, depression of ST-segment, heart failure, arrhythmias, unstable angina, hypertrophic cardio-myopathy); (6) transient ischemic attack; (7) by-pass surgery in the recent three months; and (8) other musculoskeletal problems that prevented the participants from doing aerobic activity.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Government College University Faisalabad

OTHER

Sponsor Role: lead

Responsible Party

Ishtiaq Ahmed

Physiotherapist

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Bin Inam Rehabilitation Center.

Faisalābad, Punjab Province, Pakistan

Countries

Pakistan

References

Lau KW, Mak MK. Speed-dependent treadmill training is effective to improve gait and balance performance in patients with sub-acute stroke. J Rehabil Med. 2011 Jul;43(8):709-13. doi: 10.2340/16501977-0838.

Reference Type: RESULT

PMID: 21698340 (View on PubMed)

Other Identifiers

555

Identifier Type: -

Identifier Source: org_study_id